中國藥科大學

情況簡介：

戴振亞，2000年在南京大學獲得學士學位，專業為化學，2005年10月在南京大學獲得博士學位，專業為有機化學，2005年11月至2007年8月在德國萊布尼茲催化研究所從事博士后研究，2007年8月至今在中國藥科大學擔任教師，并于2008年12月被聘為副教授。目前主持國家自然科學基金青年教師基金一項，參與江蘇省自然科學基金一項。目前發表論文23篇，其中SCI收錄16篇。聯系方式：daizhenya@hotmail.com，15951867995。

研究方向：不對稱催化，不對稱合成，手性藥物合成，藥物合成新方法研究。

發表論文目錄：

1.Jiangtao Sun, Chengjian Zhu*, Zhenya Dai, Minghua Yang, Yi Pan, Hongwen Hu. Efficient Asymmetric Oxidation of Sulfides and Kinetic Resolution of Sulfoxides Catalyzed by Vanadium Salan System. J. Org. Chem. 2004, 69, 8500-8503.
2.Zhenya Dai, Chengjian Zhu*, Minghua Yang, Yi Pan*. Asymmetric addition of organogallium to aldehydes catalyzed by chiral titanium catalyst. Tetrahedron: Asymmetry. 2005, 16，605－608.
3. Zhenya Dai, Chengjian Zhu*, Yi Pan*. Utilization of organogallium and organoindium compounds as alkylation reagents in organic synthesis: the addition of trialkylgallium and trialkylindium to aldehydes catalyzed by Lewis acids. Applied Organometallic Chemistry 2005, 7, 898-902.
4.Haibing Zhu, Zhenya Dai, Wei Huang, Kai Cui, Shaohua Gou*, Chenjian Zhu*. Chiral copper(II) complexes of optically active Schiff bases: syntheses, crystal structure and asymmetric oxidation of methyl phenyl sulfide with hydrogen peroxidePolyhedron 2004, 23, 1131-1137
5.Zhenya Dai, Detlef Heller, Anke Spannenberg, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-((+)-1,1'-bis((2R,4R)-2,4-diethyl-phosphotano)-ferrocene)-rhodium(I) tetrafluoroborate, [Rh(C8H12)Fe(C12H18FeP)2][BF4]  Z. Krist. (NCS) 2007, 222, 109.
6.Zhenya Dai, Detlef Heller, Angelika Preetz, Hans-Joachim Drexler. Crystal structure of (η4-cycloocta-1,5-dien)-N-(2-(diphenylphosphinooxy)-3-(naphthalen-1-yloxy)propyl)-N-(pentan-3-yl)-1,1-diphenylphosphinamine-rhodium(I)tetrafluoroborate, [Rh(C8H12)(C42H43NO2P2)][BF4] Z. Krist. (NCS) 2007, 222, 111.
7.Ralph Jackstell, Zhenya Dai, Thomas Schmidt, Detlef Heller, Hans-Joachim Drexler. Crystal structure of 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) norborna-2,5-diene tetrafluoroborate tetrahydrofuran hemisolvate, [Rh(C34H51NP2)(C7H8)][BF4] 0.5C4H8O, and 1-(2-(dicyclohexylphosphinophenyl)pyrol-2-dicyclohexylphosphino-rhodium(I) (Z,Z)-cycloocta-1,5-diene tetrafluoroborate, [Rh(C34H51NP2)(C8H12)][BF4] Z. Krist. (NCS) 2007, 222, 458.
8.Angelika Preetz, Hans-Joachim Drexler, Christian Fischer, Zhenya Dai, Armin Borner, Wolfgang Baumann, Anke Spannenberg, Richard Thede, Detlef Heller. Rhodium catalyst catalyzed asymmetric hydrogenation-Transfer of the precatalyst into active species. Chemistry: A European Journal 2008, 14, 1445.
9.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Wolfgang Baumann, Christian Jäger, Dietmar Pfeifer, Detlef Heller*. Novel contributions to the mechanism of the enantioselective hydrogenation of dimethyl itaconate with rhodium complexes. Chemistry: A European Journal 2008, 14, 4469-4471.
10.Thomas Schmidt, Zhenya Dai, Hans-Joachim Drexler, Detlef Heller* The major/minor concept:dependence of the selectivity of homogeneously catalyzed reactions on the reactivity ratio and concerntration of the intermediates. Chemistry: An Asian Journal 2008, 1170-1180.
11.Jiangtao Sun, Zhenya Dai, Minghua Yang, Xu Pan, Chengjian Zhu* Vanadium-salan catalyzed enantioselective ring-opening of meso-epoxides with aromatic amines. Synthesis, 2008, 13, 2100-2104.
12.Jiangtao Sun*, Minghua Yang, Zhenya Dai, Chengjian Zhu*, Hongwen Hu Synthesis of Optically Active 2,5-Dialkylcyclohexane-1,4-diols and Their Application in the Asymmetric Oxidation of Sulfides. Synthesis, 2008, 13, 2513-2518.
13.Jiangtao Sun, Xu Pan, Zhenya Dai, Chengjian Zhu* Synthesis of new Schiff base-camphorsulfonyl amide ligands and in situ screening in asymmetric addition of organozinc reagents to aldehydes. Tetrahedron: Asymmetry 2008, 19, 2451-2457.
14.Jiangtao Sun, Zhenya Dai*, Changsi Li, Xu Pan, Chengjian Zhu* Enantionselective pinacol coupling reaction of aromatic aldehydes catalyzed by chiral vanadium catalyst. Jouranl of Organometallic Chemistry 2009, 3219-3221.
15.Thomas Schmidt, Hans-Joachim Drexler, Jiangtao Sun, Zhenya Dai, Wolfgang Baumann, Angelika Preetz, Detlef Heller* Unusual Deactivation in the Asymmetric Hydrogenation of Itaconic Acid. Advanced Synthesis & Catalysis 2009, 351(5), 750-754.
16.Xiaoyang Dong, Ziyu Wang, Daorui Huang, Pei Xu, Zhenya Dai*, Synthesis of New Chiral Phase Transfer Catalysts and their Application in the Asymmetric Alkylation of Glycine Derivatives. Austin Journal of Analytical and Pharmaceutical Chemistry. 2014, 1(1), 3-5.
17.Ziyu Wang, Daorui Huang, Pei Xu, Xiaoyang Dong, Xiaolong Wang and Zhenya Dai *The asymmetric alkylation reaction of glycine derivatives catalyzed by the novel chiral phase transfer catalysts Tetrahedron Lett. 2015, 56, 1067-1071.
18.Xiaoyang Dong, Pei Xu, Ziyu Wang, Daorui Huang, Zhenya Dai*. Asymmetric sulfenylation of glycine derivative catalyzed by the novel chiral phase transfer catalysts. Austin J Anal Pharm Chem. 2015, 2(1), 1032.
19.Ziyu Wang, Xueyan Zhang, Pei Xu, Daorui Huang, Xiaolong Wang, Zhenya Dai*. Research on phase transfer catalytic reactions and their application in drug synthesis. Austin J Anal Pharm Chem. 2015, 2(1), 1033.
20.Lin Qiu, Daorui Huang, Guangyang Xu, Zhenya Dai, Jiangtao Sun*. Realized C−H Functionalization of Aryldiazo Compouds via Rhodium Relay Catalysis. Org. Lett. 2015, 17, 1810-1813.
21.李長思，戴振亞*等地爾硫卓中間體的合成工藝改進藥學與臨床研究2011,19,184-185.
22.王永超，戴振亞*等地爾硫卓中間體a,b-三元腈的合成藥學與臨床研究2011,19,470-471
23.劉洋，戴振亞*等氯沙坦合成工藝改造藥學與臨床研究2011,19,89-90
24.李長思，戴振亞*等脯氨酸催化的酮的不對稱a-硫代反應藥學與臨床研究2010,18,243-246.
25.袁飛鵬，戴振亞*等脯氨酸催化的醛的不對稱a-硫代反應藥學進展2010,34,554-558.
26.盧協勤，戴振亞*等相轉移催化的甘氨酸叔丁酯衍生物的硫代反應河北醫藥2012,34,1075-1077.
27.董曉陽，戴振亞*等不對稱小分子催化合成的最新進展及其在藥物合成中的應用中國藥科大學學報2013,44,193-201.

申報及授權專利目錄：

1.戴振亞，袁飛鵬等，羅本考昔的一種制備方法，專利授權號：CN102311355B.
2.戴振亞，袁飛鵬等，馬氟考昔的一種制備方法，專利號：201210063799.
3.戴振亞，王永超等，一種手性相轉移催化劑及其合成方法，專利號：201210085648.
4.戴振亞，王永超等，一種甘氨酸叔丁酯衍生物的不對稱烷基化方法，專利號：201210085610.
5.戴振亞，袁飛鵬等，R-4-芐氧吡咯烷的一種制備方法，專利號：201210085627.
6.王森，曹鑫，曹聰，戴振亞，陸愛軍，HDM2和HDMX雙重抑制劑3－腈基喹啉衍生物及其制備方法與應用專利授權號：CN103804292A.
7.戴振亞，董曉陽等，一種新型手性相轉移催化劑的合成及其應用，專利號：201410088280.6.
8.戴振亞，王子昱，黃道銳，徐沛一種環狀金雞納堿季銨鹽化合物的制法以及用途,專利號：201410455252.3.
9.王森，曹鑫，戴振亞，曹聰，張凌霄，(+)-生物素的制備方法，CN103833769A.
10.戴振亞，趙云德，王子昱，張學艷，許莎莎，依托考昔的一種合成方法，CN104693113A.