中國藥科大學

邢磊，男，博士，講師，碩士研究生導師。2005年畢業于河南大學藥學院藥物制劑專業，2005~2008年在河南大學藥學院攻讀藥劑學碩士學位，其中2006.7~2008.5期間在軍事醫學科學院金義光課題組從事自組裝藥物傳遞系統的研究；2008年考入上海交通大學化學化工學院，師從車順愛教授，研究方向為pH響應性配位聚合物用于藥物傳遞的研究，主要參與《國家973項目--納米結構材料的程序化組裝》和《重大新型藥物開發項目》。2012年9月加入中國藥科大學藥學院藥劑教研室從事教學科研工作。目前已在SCI期刊上發表較高水平論文13篇。主持和參與的國家自然科學基金6項，江蘇省自然基金3項。主持國重優秀青年人才基金1項。

研究方向：藥用高分子材料與靶向釋藥系統研究；配位藥物遞送系統研究；聚合物藥物遞送系統研究

近期發表的文章：

1. Zhang BF†, Xing L†, Cui PF, Wang FZ, Xie RL, Zhang JL, Zhang M, He YJ, Lyu JY, Qiao JB, Chen BA, Jiang HL*. Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine. Biomaterials. 2015, 61: 178-189. (†equal contribution)

2. Kim YK†, Zhang M†, Zhang BF, Wang FZ, Cui PF, Xie RL, Xing L*, and Jiang HL*. Hepatic Targeting Gene Delivery Using Galactosylated Ester-Based Polyspermine. J. Nanosci. Nanotechnol. 2015, doi:10.1166/jnn.2015.11341.

3. Kim YK†, Xing L†, Chen BA, Xu FG, Jiang HL*, Zhang C*. Aerosol delivery of programmed cell death protein 4 using polysorbitol-based gene delivery system for lung cancer therapy. J. Drug Target. 2014, 22(9): 829-838. (†equal contribution)

4. Xie RL†, Jang YJ†, Xing L, Zhang BF, Wang FZ, Cui PF, Cho MH*, Jiang HL*. A novel potential biocompatible hyperbranched polyspermine for efficient lung cancer gene therapy. Int. J. Pharm. 2014, 478(1): 19-30.

5. Su Z†, Xing L†, Chen Y, Xu Y, Yang F, Zhang C, Ping Q, Xiao Y*. Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas. Mol. Pharm. 2014, 11(6): 1823-34. (†equal contribution)

6. Zheng H., Xing L, Cao Y, and Che S*, Coordination bonding based pH-responsive drug delivery systems, Coordin. Chem. Rev. 2013, 257: 1933-1944.

7. Xing L, Zheng H, Cao Y, Che S*, Coordination Polymer Coated Mesoporous Silica Nanoparticles for pH-Responsive Drug Release, Adv. Mater. 2012. 24: 6433-6437.

8.  Xing L, Cao Y, Che S*, Synthesis of Core-Shell Coordination Polymer Nanoparticles (CPNs) for pH-responsive Controlled Drug Release, Chem. Commun. 2012. 48: 5995-5997.

9. Xing L, Zheng H, Che S*, A pH-responsive Cleavage Route Based On a Metal-Organic Coordination Bonding, Chem. Eur. J. 2011, 17: 7271-7275.

10. Gao C†, Zheng H†, Xing L†, Shu M and Che S*, Designable Coordination Bonding in Mesopores as a pH-Responsive Release System, Chem. Mater. 2010, 22: 5437-5444. (†equal contribution)

11. Li C, Xing L and Che S*, Coordination Bonding Based pH-Responsive Albumin Nanoparticles for Anticancer Drug Delivery, Dalton T. 2012, 41: 3714-3719.

12. Ma Y, Xing L, Zheng H and Che S*, Anionic-Cationic Switchable Amphoteric Monodisperse Mesoporous Silica Nanoparticles, Langmuir, 2011, 27: 517-520.

13. Jin Y*, Xing L, Tian Y, Li M, Gao C, Du L, Dong J* and Chen H, Self-assembled drug delivery systems. Part 4. In vitro/in vivo studies of the self-assemblies of cholesteryl-phosphonyl zidovudine. Int. J. Pharm. 2009, 345: 40-48.

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