中國科學技術大學

湯朝暉
單位：中國科學院長春應用化學研究所生態環境高分子材料重點實驗室
地址：吉林省長春市人民大街5625號
郵編：130022
電話：0431-85262116

個人簡歷  Personalresume 
湯朝暉博士研究員
工作單位：中國科學院長春應用化學研究所，生態環境高分子材料重點實驗室
學習經歷
1999–2005中國科學院長春應用化學研究所，高分子化學與物理專業，理學博士，導師：陳學思研究員；
1995–1999湘潭大學化學系，理學學士；
工作經歷
2015–研究員，中國科學院長春應用化學研究所；
2009–2014副研究員，中國科學院長春應用化學研究所；
2007–2008博士后，美國紐約州立大學石溪分校（StateUniversityofNewYorkatStonyBrook），合作導師：朱鵬年（BenjaminChu），蕭守道（BenjaminS.Hsiao）；
2005–2006研究助理，英國帝國理工學院（ImperialCollegeLondon），合作導師：VCGibson。
研究興趣
生物醫用高分子材料，藥物緩控釋
學術論文與專利情況
發表SCI研究論文80余篇，包括ProgressinPolymerScience,ChemicalScience,Biomateials,JournalofControlledRelease等，他引2000余次，授權專利30項。
個人榮譽
1. 2015年入選中國科學院青年創新促進會優秀會員；
2. 2011年入選中國科學院青年創新促進會會員；
3. 湯朝暉，可降解醫用高分子材料的基礎及應用研究，吉林省科技進步獎，一等獎，排名第7，2011。
4. 湯朝暉，聚乳酸新材料關鍵技術研發與產業化應用，中國石油與化學工業聯合會技術發明獎，一等獎，排名第6，2011。

主持或參加科研項目（課題）
1. 國家自然科學基金面上項目，2016年，高分子納米化CD47抗體用于惡性腫瘤的研究，62萬元，主持；
2. 中國科學院青年創新促進會優秀會員，2015年，優秀會員人才專項經費，150萬元，主持；
3. 國家自然科學基金面上項目，51373168，物理化學性質和腫瘤種類對高分子納米粒子在小鼠體內代謝和分布的影響研究，2014/01–2017/12，80萬元，主持；
4. 國家科技重大專項重大新藥創制，2014ZX09507-009，IPT-ZHW155的臨床前研究，2014/01–2016/12，40.5萬元，參加（子課題副組長）；
5. 吉林省醫藥產業發展專項資金項目，20130727050YY，聚谷氨酸接枝聚乙二醇藥用輔料及順鉑膠束制劑的研究和開發，2013/06–2016/05，50萬元，主持；
6. 國家科技重大專項重大新藥創制，2013ZX09J13110-11B，基于生物可降解高分子電紡絲技術的戰傷救治藥物體系，2013/01–2015/12，110萬元參加（子課題副組長）；
7. 吉林省科技發展計劃項目，科技支撐計劃，重點科技攻關項目，20130206066GX，用于抗腫瘤藥物靶向控釋的高分子載體材料的研究和開發，2013/01–2015/12，18萬元，主持；
8. 國家自然科學基金面上項目，51173184，氧化還原和pH雙敏感的納米藥物控釋系統及其克服腫瘤多藥耐藥性研究，2012/01–2015/12，65萬元，主持；
9. 中國科學院青年創新促進會會員，2011年，會員人才專項經費，40萬元，主持；
10. 國家自然科學青年基金，2009年，具有生物分子識別功能可生物降解高分子材料的合成與應用，23萬元，主持。
學術論文與書籍章節目錄
[1]Y.Zhang,C.Xiao,J.Ding,M.Li,X.Chen,Z.Tang,X.Zhuang,X.Chen,Acomparativestudyoflinear,Y-shapedandlinear-dendriticmethoxypoly(ethyleneglycol)-block-polyamidoamine-block-poly(l-glutamicacid)blockcopolymersfordoxorubicindeliveryinvitroandinvivo,ActaBiomater.40(2016)243-253.
[2]H.Yu,Z.Tang,M.Li,W.Song,D.Zhang,Y.Zhang,Y.Yang,H.Sun,M.Deng,X.Chen,Cisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesforpotentialcancertherapy:preparation,invitroandinvivoevaluation,JBiomedNanotechnol.12(1)(2016)69-78.
[3]Y.Wang,S.Lv,M.Deng,Z.Tang,X.Chen,Acharge-conversionalintracellular-activatedpolymericprodrugfortumortherapy,Polym.Chem.7(2016)2253-2263.
[4]Z.Tang,C.He,H.Tian,J.Ding,B.S.Hsiao,B.Chu,X.Chen,Polymericnanostructuredmaterialsforbiomedicalapplications,Prog.Polym.Sci.60(2016)86-128.
[5]W.Song,Z.Tang,D.Zhang,X.Wen,S.Lv,Z.Liu,M.Deng,X.Chen,SolidTumorTherapyUsingaCannonandPawnCombinationStrategy,Theranostics6(7)(2016)1023-1030.
[6]W.Song,Z.Tang,D.Zhang,M.Li,J.Gu,X.Chen,Acooperativepolymericplatformfortumor-targeteddrugdelivery,ChemicalScience7(1)(2016)728-736.
[7]W.Song,Z.Tang,N.Shen,H.Yu,Y.Jia,D.Zhang,J.Jiang,C.He,H.Tian,X.Chen,Combiningdisulfiramandpoly(l-glutamicacid)-cisplatinconjugatesforcombatingcisplatinresistance,J.Control.Release231(2016)94-102.
[8]W.Song,Z.Tang,T.Lei,X.Wen,G.Wang,D.Zhang,M.Deng,X.Tang,X.Chen,StableloadinganddeliveryofdisulfiramwithmPEG-PLGA/PCLmixednanoparticlesfortumortherapy,Nanomed.Nanotechnol.Biol.Med.12(2)(2016)377-86.
[9]Y.Niu,W.Song,D.Zhang,Z.Tang,M.Deng,X.Chen,Functionalcomputer-to-platenear-infraredabsorbersashighlyefficientphotoacousticdyes,ActaBiomater.43(2016)262-8.
[10]C.He,Z.Tang,H.Tian,X.Chen,Co-deliveryofchemotherapeuticsandproteinsforsynergistictherapy,Adv.DrugDel.Rev.98(2016)64-76.
[11]J.Chen,L.Lin,Z.Guo,C.Xu,Y.Li,H.Tian,Z.Tang,C.He,X.Chen,N-IsopropylacrylamideModifiedPolyethyleniminesasEffectivesiRNACarriersforCancerTherapy,JournalofNanoscienceandNanotechnology16(6)(2016)5464-5469.
[12]Z.Ahmad,S.Lv,Z.Tang,A.Shah,X.Chen,Methoxypoly(ethyleneglycol)-block-poly(glutamicacid)-graft-6-(2-nitroimidazole)hexylaminenanoparticlesforpotentialhypoxia-responsivedeliveryofdoxorubicin,J.Biomater.Sci.Polym.Ed.27(1)(2016)40-54.
[13]馬麗莉,邵俊,楊晨光,湯朝暉,陳學思,PDLA-PBS-PDLA三嵌段共聚物的合成及性能,高等學校化學學報36(11)(2015)2329-2334.
[14]H.Yu,Z.Tang,D.Zhang,W.Song,Y.Zhang,Y.Yang,Z.Ahmad,X.Chen,Pharmacokinetics,biodistributionandinvivoefficacyofcisplatinloadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)complexnanoparticlesfortumortherapy,J.Control.Release205(2015)89-97.
[15]H.Yu,Z.Tang,D.Zhang,W.Song,T.Duan,J.Gu,X.Chen,Poly(ornithine‐co‐arginine‐co‐glycine‐co‐asparticAcid):PreparationviaNCAPolymerizationanditsPotentialasaPolymericTumor‐PenetratingAgent,Macromol.Biosci.15(6)(2015)829–838.
[16]H.Yu,Z.Tang,W.Song,D.Zhang,Y.Zhang,X.Chen,Co-administrationofiRGDenhancingtheanticancerefficacyofcisplatin-loadedpolypeptidenanoparticles,J.Control.Release213(2015)e145-e146.
[17]H.Y.YifeiLi,HaiSun,JianguoLiu,ZhaohuiTang,DanWang,LianyouYu,XuesiChen,Cisplatin-loadedpoly(L-glutamicacid)-g-methoxypoly(ethyleneglycol)nanoparticlesasapotentialchemotherapeuticagentagainstosteosarcoma,Chin.J.Polym.Sci.33(5)(2015)763-771.
[18]W.Song,Z.Tang,D.Zhang,H.Yu,X.Chen,CoadministrationofVascularDisruptingAgentsandNanomedicinestoEradicateTumorsfromPeripheralandCentralRegions,Small11(31)(2015)3755-3761.
[19]W.Song,Z.Tang,D.Zhang,N.Burton,W.Driessen,X.Chen,Comprehensivestudiesofpharmacokineticsandbiodistributionofindocyaninegreenandliposomalindocyaninegreenbymultispectraloptoacoustictomography,RSCAdv.5(5)(2015)3807-3813.
[20]C.Shi,H.Yu,D.Sun,L.Ma,Z.Tang,Q.Xiao,X.Chen,Cisplatin-loadedpolymericnanoparticles:Characterizationandpotentialexploitationforthetreatmentofnon-smallcelllungcarcinoma,ActaBiomater.18(2015)68–76.
[21]M.Q.Li,Z.H.Tang,Y.Zhang,S.X.Lv,Q.S.Li,X.S.Chen,TargeteddeliveryofcisplatinbyLHRH-peptideconjugateddextrannanoparticlessuppressesbreastcancergrowthandmetastasis,ActaBiomater.18(2015)132-143.
[22]M.Li,Z.Tang,D.Zhang,H.Sun,H.Liu,Y.Zhang,Y.Zhang,X.Chen,Doxorubicin-loadedpolysaccharidenanoparticlessuppressthegrowthofmurinecolorectalcarcinomaandinhibitthemetastasisofmurinemammarycarcinomainrodentmodels,Biomaterials51(0)(2015)161-172.
[23]B.Feng,Z.Xu,F.Zhou,H.Yu,Q.Sun,D.Wang,Z.Tang,H.Yu,Q.Yin,Z.Zhang,Y.Li,Nearinfraredlight-actuatedgoldnanorodswithcisplatin-polypeptidewrappingfortargetedtherapyoftriplenegativebreastcancer,Nanoscale7(36)(2015)14854-64.
[24]R.Zhao,X.Li,B.Sun,Y.Zhang,D.Zhang,Z.Tang,X.Chen,C.Wang,Electrospunchitosan/sericincompositenanofiberswithantibacterialpropertyaspotentialwounddressings,Int.J.Biol.Macromol.68(2014)92-97.
[25]H.Yu,Z.Tang,W.Song,M.Deng,X.Chen,CurrentStatusandFutureProspectsofPolymericNanocarrierforTumorTargeting,Chem.J.Chin.Univ.-Chin.35(5)(2014)903-916.
[26]W.Song,Z.Tang,D.Zhang,Y.Zhang,H.Yu,M.Li,S.Lv,H.Sun,M.Deng,X.Chen,Anti-tumorefficacyofc(RGDfK)-decoratedpolypeptide-basedmicellesco-loadedwithdocetaxelandcisplatin,Biomaterials35(9)(2014)3005-3014.
[27]W.Song,Z.Tang,M.Li,S.Lv,H.Sun,M.Deng,H.Liu,X.Chen,Polypeptide-basedcombinationofpaclitaxelandcisplatinforenhancedchemotherapyefficacyandreducedside-effects,ActaBiomater.10(3)(2014)1392-1402.
[28]J.Shao,Z.Tang,J.Sun,G.Li,X.Chen,LinearandFour-ArmedPoly(L-lactide)-block-poly(D-lactide)CopolymersandTheirStereocomplexationwithPoly(lactide)s,JournalofPolymerSciencePartB-PolymerPhysics52(23)(2014)1560-1567.
[29]Z.Qu,R.Duan,X.Pang,B.Gao,X.Li,Z.Tang,X.Wang,X.Chen,LivingandStereoselectivePolymerizationofRac-LactidebyBimetallicAluminumSchiff-BaseComplexes,JournalofPolymerScienceParta-PolymerChemistry52(9)(2014)1344-1352.
[30]S.Lv,Z.Tang,D.Zhang,W.Song,M.Li,J.Lin,H.Liu,X.Chen,Well-definedpolymer-drugconjugateengineeredwithredoxandpH-sensitivereleasemechanismforefficientdeliveryofpaclitaxel,J.Control.Release194(2014)220-227.
[31]S.Lv,Z.Tang,M.Li,J.Lin,W.Song,H.Liu,Y.Huang,Y.Zhang,X.Chen,Co-deliveryofdoxorubicinandpaclitaxelbyPEG-polypeptidenanovehicleforthetreatmentofnon-smallcelllungcancer,Biomaterials35(23)(2014)6118-6129.
[32]S.Lv,W.Song,Z.Tang,M.Li,H.Yu,H.Hong,X.Chen,Charge-ConversionalPEG-PolypeptidePolyionicComplexNanoparticlesfromSimpleBlendingofaPairofOppositelyChargedBlockCopolymersasanIntelligentVehicleforEfficientAntitumorDrugDelivery,Mol.Pharm.11(5)(2014)1562-1574.
[33]Q.Li,S.Lv,Z.Tang,M.Liu,D.Zhang,Y.Yang,X.Chen,Aco-deliverysystembasedonpaclitaxelgraftedmPEG-b-PLGloadedwithdoxorubicin:Preparation,invitroandinvivoevaluation,Int.J.Pharm.471(1–2)(2014)412-420.
[34]M.-q.Li,Z.-h.Tang,C.Wang,Y.Zhang,H.-t.Cui,X.-s.Chen,Efficientside-chainmodificationofdextranviabase-catalyzedepoxidering-openingandthiol-eneclickchemistryinaqueousmedia,Chin.J.Polym.Sci.32(8)(2014)969-974.
[35]M.Li,Z.Tang,Y.Zhang,S.Lv,H.Yu,D.Zhang,H.Hong,X.Chen,LHRH-peptideconjugateddextrannanoparticlesfortargeteddeliveryofcisplatintobreastcancer,J.Mat.Chem.B2(22)(2014)3490-3499.
[36]M.Li,Z.Tang,S.Lv,W.Song,H.Hong,X.Jing,Y.Zhang,X.Chen,CisplatincrosslinkedpH-sensitivenanoparticlesforefficientdelivery.ofdoxorubicin,Biomaterials35(12)(2014)3851-3864.
[37]M.Li,Z.Tang,J.Lin,Y.Zhang,S.Lv,W.Song,Y.Huang,X.Chen,SynergisticAntitumorEffectsofDoxorubicin-LoadedCarboxymethylCelluloseNanoparticleinCombinationwithEndostarforEffectiveTreatmentofNon-Small-CellLungCancer,Adv.Healthc.Mater.3(11)(2014)1877-1888.
[38]Z.Guo,H.Tian,L.Lin,J.Chen,C.He,Z.Tang,X.Chen,HydrophobicPolyalanineModifiedHyperbranchedPolyethylenimineasHighEfficientpDNAandsiRNACarrier,Macromol.Biosci.14(10)(2014)1406-1414.
[39]J.Chen,J.Xia,H.Tian,Z.Tang,C.He,X.Chen,Thermo-/pH-dualresponsivepropertiesofhyperbranchedpolyethyleniminegraftedbyphenylalanine,Arch.Pharm.Res.37(1)(2014)142-148.
[40]Z.Ahmad,Z.Tang,A.Shah,S.Lv,D.Zhang,Y.Zhang,X.Chen,CisplatinLoadedMethoxyPoly(ethyleneglycol)-block-Poly(L-glutamicacid-co-L-Phenylalanine)NanoparticlesagainstHumanBreastCancerCell,Macromol.Biosci.14(9)(2014)1337-1345.
[41]L.Zhao,C.Xiao,J.Ding,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Facileone-potsynthesisofglucose-sensitivenanogelviathiol-eneclickchemistryforself-regulateddrugdelivery,ActaBiomater.9(5)(2013)6535-6543.
[42]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Chen,Phenylboronicacidfunctionalizedpolypeptidemicellesforglucose-responsiveinsulinreleaseatphysiologicalpH,J.Control.Release172(1)(2013)E110-E110.
[43]S.Lv,M.Li,Z.Tang,W.Song,H.Sun,H.Liu,X.Chen,Doxorubicin-loadedamphiphilicpolypeptide-basednanoparticlesasanefficientdrugdeliverysystemforcancertherapy,ActaBiomater.9(12)(2013)9330-9342.
[44]M.Li,Z.Tang,H.Sun,J.Ding,W.Song,X.Chen,pHandreductiondual-responsivenanogelcross-linkedbyquaternizationreactionforenhancedcellularinternalizationandintracellulardrugdelivery,Polym.Chem.4(4)(2013)1199-1207.
[45]M.Li,W.Song,Z.Tang,S.Lv,L.Lin,H.Sun,Q.Li,Y.Yang,H.Hong,X.Chen,NanoscaledPoly(L-glutamicacid)/Doxorubicin-AmphiphileComplexaspH-responsiveDrugDeliverySystemforEffectiveTreatmentofNonsmallCellLungCancer,AcsAppliedMaterials&Interfaces5(5)(2013)1781-1792.
[46]M.Li,S.Lv,Z.Tang,W.Song,H.Yu,H.Sun,H.Liu,X.Chen,Polypeptide/DoxorubicinHydrochloridePolymersomesPreparedThroughOrganicSolvent-freeTechniqueasaSmartDrugDeliveryPlatform,Macromol.Biosci.13(9)(2013)1150-1162.
[47]D.Li,H.Sun,J.Ding,Z.Tang,Y.Zhang,W.Xu,X.Zhuang,X.Chen,Polymerictopologyandcompositionconstrainedpolyether-polyestermicellesfordirectionalantitumordrugdelivery,ActaBiomater.9(11)(2013)8875-8884.
[48]Y.Huang,Z.Tang,X.Zhang,H.Yu,H.Sun,X.Pang,X.Chen,pH-TriggeredCharge-ReversalPolypeptideNanoparticlesforCisplatinDelivery:PreparationandInVitroEvaluation,Biomacromolecules14(6)(2013)2023-2032.
[49]P.He,C.-w.Zhao,C.-s.Xiao,Z.-h.Tang,X.-s.Chen,Thermosensitivepolyioncomplexmicellespreparedbyself-assemblyoftwooppositelychargeddiblockcopolymers,Chin.J.Polym.Sci.31(2)(2013)318-324.
[50]P.He,H.Liu,Z.Tang,M.Deng,Y.Yang,X.Pang,X.Chen,Poly(esteramide)blendmicrospheresfororalinsulindelivery,Int.J.Pharm.455(1-2)(2013)259-266.
[51]C.He,Z.Tang,H.Tian,X.Chen,ProgressintheDevelopmentofBiomedicalPolymerMaterialsFabricatedby3-DimensionalPrintingTechnology,ActaPolymericaSinica(6)(2013)722-732.
[52]J.Guo,X.Li,H.Yu,Z.Tang,X.Tang,C.Cai,J.Xu,H.Xu,Theanti-melanomaefficiencyoftheintratumoralinjectionofcucurbitacin-loadedsustained-releasecarriers:APLGAparticlesystem,J.Pharm.Sci.102(8)(2013)2550-2563.
[53]B.Gao,R.Duan,X.Pang,X.Li,Z.Qu,Z.Tang,X.Zhuang,X.Chen,StereoselectiveRing-OpeningPolymerizationofrac-LactidesCatalyzedbyAluminumHemi-SalenComplexes,Organometallics32(19)(2013)5435-5444.
[54]L.Zhao,J.Ding,C.Xiao,P.He,Z.Tang,X.Pang,X.Zhuang,X.Chen,Glucose-sensitivepolypeptidemicellesforself-regulatedinsulinreleaseatphysiologicalpH,J.Mater.Chem.22(24)(2012)12319-12328.
[55]H.Tian,Z.Tang,X.Zhuang,X.Chen,X.Jing,Biodegradablesyntheticpolymers:Preparation,functionalizationandbiomedicalapplication,Prog.Polym.Sci.37(2)(2012)237-280.
[56]W.Song,C.Xiao,L.Cui,Z.Tang,X.Zhuang,X.Chen,FacileconstructionoffunctionalbiosurfaceviaSI-ATRPand"clickglycosylation",ColloidSurf.B-Biointerfaces93(2012)188-194.
[57]W.Song,Z.Tang,M.Li,S.Lv,H.Yu,L.Ma,X.Zhuang,Y.Huang,X.Chen,TunablepH-SensitivePoly(beta-aminoester)sSynthesizedfromPrimaryAminesandDiacrylatesforIntracellularDrugDelivery,Macromol.Biosci.12(10)(2012)1375-1383.
[58]W.Song,M.Li,Z.Tang,Q.Li,Y.Yang,H.Liu,T.Duan,H.Hong,X.Chen,Methoxypoly(ethyleneglycol)-block-Poly(L-glutamicacid)-LoadedCisplatinandaCombinationWithiRGDfortheTreatmentofNon-Small-CellLungCancers,Macromol.Biosci.12(11)(2012)1514-1523.
[59]D.Li,J.X.Ding,Z.H.Tang,H.Sun,X.L.Zhuang,J.Z.Xu,X.S.Chen,InvitroevaluationofanticancernanomedicinesbasedondoxorubicinandamphiphilicY-shapedcopolymers,Int.J.Nanomedicine7(2012)2687-2697.
[60]P.He,Z.Tang,L.Lin,M.Deng,X.Pang,X.Zhuang,X.Chen,NovelBiodegradableandpH-SensitivePoly(esteramide)MicrospheresforOralInsulinDelivery,Macromol.Biosci.12(4)(2012)547-556.
[61]C.He,X.Zhuang,Z.Tang,H.Tian,X.Chen,Stimuli-SensitiveSyntheticPolypeptide-BasedMaterialsforDrugandGeneDelivery,Adv.Healthc.Mater.1(1)(2012)48-78.
[62]湯朝暉,陳學思,新型藥控/緩釋材料,中國新材料產業發展報告（2010）2011.
[63]X.-l.Zhuang,H.-y.Yu,Z.-h.Tang,K.Oyaizu,H.Nishide,X.-s.Chen,PolymerizationoflacticO-carboxylicanhydrideusingorganometalliccatalysts,Chin.J.Polym.Sci.29(2)(2011)197-202.
[64]L.Zhao,J.Ding,P.He,C.Xiao,Z.Tang,X.Zhuang,X.Chen,AnefficientpHsensitiveoralinsulindeliverysystemenhancedbydeoxycholicacid,J.Control.Release152(2011)E184-E186.
[65]W.Wang,J.Ding,C.Xiao,Z.Tang,D.Li,J.Chen,X.Zhuang,X.Chen,SynthesisofAmphiphilicAlternatingPolyesterswithOligo(ethyleneglycol)SideChainsandPotentialUseforSustainedReleaseDrugDelivery,Biomacromolecules12(7)(2011)2466-2474.
[66]J.Ding,X.Zhuang,C.Xiao,Y.Cheng,L.Zhao,C.He,Z.Tang,X.Chen,Preparationofphoto-cross-linkedpH-responsivepolypeptidenanogelsaspotentialcarriersforcontrolleddrugdelivery,J.Mater.Chem.21(30)(2011)11383-11391.
[67]J.Ding,C.Xiao,L.Zhao,Y.Cheng,L.Ma,Z.Tang,X.Zhuang,X.Chen,Poly(L-glutamicacid)GraftedwithOligo(2-(2-(2-methoxyethoxy)ethoxy)ethylmethacrylate):ThermalPhaseTransition,SecondaryStructure,andSelf-Assembly,JournalofPolymerScienceParta-PolymerChemistry49(12)(2011)2665-2676.
[68]J.Ding,C.Xiao,L.Yan,Z.Tang,X.Zhuang,X.Chen,X.Jing,pHanddualredoxresponsivenanogelbasedonpoly(l-glutamicacid)aspotentialintracellulardrugcarrier,J.Control.Release152(2011)E11-E13.
[69]J.Ding,C.Xiao,Z.Tang,X.Zhuang,X.Chen,HighlyEfficient"GraftingFrom"analpha-HelicalPolypeptideBackbonebyAtomTransferRadicalPolymerization,Macromol.Biosci.11(2)(2011)192-198.
[70]C.Xiao,C.Zhao,P.He,Z.Tang,X.Chen,X.Jing,FacileSynthesisofGlycopolypeptidesbyCombinationofRing-OpeningPolymerizationofanAlkyne-SubstitutedN-carboxyanhydrideandClick"Glycosylation",Macromol.RapidCommun.31(11)(2010)991-997.
[71]F.Wan,Z.Tang,W.He,B.Chu,Achemistry/physicspathwaywithnanofibrousscaffoldsforgenedelivery,PCCP12(39)(2010)12379-12389.
[72]X.Pang,X.Zhuang,Z.Tang,X.Chen,Polylacticacid(PLA):Research,developmentandindustrialization,BiotechnologyJournal5(11)(2010)1125-1136.
[73]Z.H.Tang,C.Q.Qiu,J.R.McCutcheon,K.Yoon,H.Y.Ma,D.F.Fang,E.Lee,C.Kopp,B.S.Hsiao,B.Chu,DesignandFabricationofElectrospunPolyethersulfoneNanofibrousScaffoldforHigh-FluxNanofiltrationMembranes,JournalofPolymerSciencePartB-PolymerPhysics47(22)(2009)2288-2300.
[74]Z.Tang,J.Wei,L.Yung,B.Ji,H.Ma,C.Qiu,K.Yoon,F.Wan,D.Fang,B.S.Hsiao,B.Chu,UV-curedpoly(vinylalcohol)ultrafiltrationnanofibrousmembranebasedonelectrospunnanofiberscaffolds,J.Membr.Sci.328(1-2)(2009)1-5.
[75]Z.Tang,V.C.Gibson,rac-Lactidepolymerizationusingaluminumcomplexesbearingtetradentatephenoxy-amineligands,Eur.Polym.J.43(1)(2007)150-155.
[76]Y.K.Yang,Z.H.Tang,X.Pang,H.Z.Du,X.S.Chen,X.B.Jing,Stereoselectivepolymerizationofrac-lactideinitiatedbyachiralSchiff-baseisopropoxidealuminumcomplex,Chem.J.Chin.Univ.-Chin.27(2)(2006)352-355.
[77]Z.Tang,X.Pang,J.Sun,H.Du,X.Chen,Five-coordinatedactivespeciesinthestereoselectivepolymerizationofrac-lactideusingN,N'-(2,2-dimethyl-1,3-propylene)bis(3,5-di-tert-butyl-salicylideneimine)aluminumcomplexes,JournalofPolymerScienceParta-PolymerChemistry44(16)(2006)4932-4938.
[78]Z.H.Tang,Y.K.Yang,X.Pang,J.L.Hu,X.S.Chen,N.H.Hu,X.B.Jing,Controlledandstereospecificpolymerizationofrac-lactidewithasingle-siteethylaluminumandalcoholinitiatingsystem,J.Appl.Polym.Sci.98(1)(2005)102-108.
[79]J.L.Hu,Z.H.Tang,X.Y.Qiu,X.Pang,Y.K.Yang,X.S.Chen,X.B.Jing,Formationofflower-orcake-shapedstereocomplexparticlesfromthestereomultiblockcopoly(rac-lactide)s,Biomacromolecules6(5)(2005)2843-2850.
[80]J.Hu,Z.Tang,X.Qiu,Y.Han,Q.Du,X.Chen,X.Jing,EffectsofStereoregularityofMultiblockCopoly(rac-lactide)sonStereocomplexMicroparticlesandTheirInsulinDelivery,Macromol.Biosci.5(12)(2005)1193-1199.
[81]H.L.Guan,Z.G.Xie,Z.H.Tang,X.Y.Xu,X.S.Chen,X.B.Jing,Preparationofblockcopolymerofepsilon-caprolactoneand2-methyl-2-carboxyl-propylenecarbonate,Polymer46(8)(2005)2817-2824.
[82]C.Deng,G.Z.Rong,H.Y.Tian,Z.H.Tang,X.S.Chen,X.B.Jing,Synthesisandcharacterizationofpoly(ethyleneglycol)-b-poly(L-lactide)-b-poly(L-glutamicacid)triblockcopolymer,Polymer46(3)(2005)653-659.
[83]Z.H.Tang,X.S.Chen,Y.K.Yang,X.Pang,J.R.Sun,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactidewithabulkyaluminum/Schiffbasecomplex,JournalofPolymerScienceParta-PolymerChemistry42(23)(2004)5974-5982.
[84]Z.H.Tang,X.S.Chen,X.Pang,Y.K.Yang,X.F.Zhang,X.B.Jing,Stereoselectivepolymerizationofrac-lactideusingamonoethylaluminumSchiffbasecomplex,Biomacromolecules5(3)(2004)965-970.
[85]J.R.Sun,Z.K.Hong,L.X.Yang,Z.H.Tang,X.S.Chen,X.B.Jing,Studyoncrystallinemorphologyofpoly(L-lactide)-poly(ethyleneglycol)diblockcopolymer,Polymer45(17)(2004)5969-5977.
[86]Z.H.Tang,X.S.Chen,Q.Z.Hang,X.C.Bian,L.X.Yang,L.H.Piao,X.B.Jing,Strontium-basedinitiatorsystemforring-openingpolymerizationofcyclicesters,JournalofPolymerScienceParta-PolymerChemistry41(13)(2003)1934-1941.
[87]G.Z.Rong,M.X.Deng,C.Deng,Z.H.Tang,L.H.Piao,X.S.Chen,X.B.Jing,Synthesisofpoly(epsilon-caprolactone)-b-poly(gamma-benzyl-L-glutamicacid)blockcopolymerusingaminoorganiccalciumcatalyst,Biomacromolecules4(6)(2003)1800-1804.
專利目錄（部分）
1. 湯朝暉；孫環嬌；于海洋；呂世賢；張大為；陳學思一種高分子抗腫瘤前藥及其制備方法.CN201410417521.7,2014.
2. 湯朝暉;李明強;于海洋;宋萬通;陳學思改性聚多糖及其制備方法.CN201410133893.7,2014.
3. 湯朝暉;李明強;林堅;宋萬通;陳學思聚多巴胺納米粒子的應用.CN201410177537.5,2014.
4. 湯朝暉;李明強;高中輝;于海洋;陳學思一種聚苯胺納米粒子的制備方法及其應用.CN201410177564.2,2014.
5. 湯朝暉；于海洋；宋萬通；李明強；陳學思阿霉素復合物及其制備方法.CN201310002466.0,2013.
6. 湯朝暉；宋萬通；于海洋；李明強；陳學思二氯-1,2-環己二胺合鉑配合物及其制備方法.CN201310361430.1,2013.
7. 湯朝暉；呂世賢；陳學思；李明強；宋萬通；于海洋氨基酸嵌段共聚物及其制備方法和復合物.CN201310009638.7,2013.
8. 湯朝暉；李明強；宋萬通；陳學思一種二價雙核鉑配合物及其制備方法.CN201310361461.7,2013.
9. 湯朝暉；李明強；陳學思；張影乙二胺四乙酸雙核鉑配合物及其制備方法.CN201310449569.1,2013.
10. 湯朝暉;李雪;于海洋;張大為;宋萬通;陳學思一種創傷止血敷料的制備方法.CN201310547279.0,2013.
11. 湯朝暉;李明強;林堅;宋萬通;呂世賢;陳學思共擔載順鉑和阿霉素的復合物、膠束及膠束的制備方法.CN201310039396.6,2013.
12. 孫海;湯朝暉;許午;高戰團;莊秀麗;陳學思一種紫杉醇高分子鍵合藥及其制備方法.CN201310588848.6,2013.
13. 湯朝暉;于海洋;宋萬通;李明強;莊秀麗;陳學思順鉑配合物及其制備方法.CN201210382696.X,2012.
14. 湯朝暉;宋萬通;呂世賢;于海洋;陳學思一種聚乙二醇-聚β-胺酯嵌段共聚物及其制備方法.CN201210311209.0,2012.
15. 湯朝暉;宋萬通;李明強;丁建勛;于海洋;陳學思一種聚氨基酸接枝共聚物及其制備方法.CN201210391089.X,2012.
16. 湯朝暉;李明強;宋萬通;呂世賢;陳學思;莊秀麗阿霉素納米粒及其制備方法.CN201210034414.7,2012.
17. 湯朝暉;李明強;宋萬通;丁建勛;陳學思;莊秀麗阿霉素復合物、膠束及膠束的制備方法.CN201210034443.3,2012.
18. 湯朝暉;李明強;宋萬通;陳學思;陳杰;莊秀麗順鉑配合物及其制備方法.CN201210034430.6,2012.
19. 湯朝暉;黃月;陳學思一種順鉑配合物及其制備方法.CN201210430624.8,2012.
20. 陳學思;趙麗;肖春生;丁建勛;何盼;湯朝暉聚合物、葡萄糖納米凝膠、葡萄糖納米凝膠組合物及其制備方法.CN201210512665.1,2012.
21. 莊秀麗;丁建勛;肖春生;賀超良;湯朝暉;陳學思聚氨基酸接枝共聚物及其制備方法.CN201110023705.1,2011.
22. 莊秀麗;丁建勛;栗迪;湯朝暉;陳學思聚氨基酸嵌段共聚物及其制備方法.CN201110343619.9,2011.
23. 湯朝暉;趙麗;丁建勛;肖春生;何盼;陳學思共聚物、葡萄糖敏感膠束、葡萄糖敏感載藥膠束及其制備方法.CN201110260560.7,2011.
24. 湯朝暉;趙麗;丁建勛;何盼;肖春生;莊秀麗;陳學思一種胰島素載藥微球及其制備方法.CN201110023708.5,2011.
25. 湯朝暉;栗迪;丁建勛;孫海;莊秀麗;陳學思嵌段共聚物及其制備方法.CN201110325770.X,2011.
26. 湯朝暉;栗迪;丁建勛;孫海;莊秀麗;陳學思抗腫瘤前藥及其制備方法.CN201110149748.4,2011.
27. 陳學思;何盼;湯朝暉;莊秀麗;林琳胰島素載藥微球及其制備方法.CN201110368851.8,2011.
28. 莊秀麗;高曉曄;湯朝暉;陳學思一種聚(L-谷氨酸)/聚丙烯酸水凝膠及其制備方法.CN201010130914.1,2010.
29. 莊秀麗;丁建勛;趙麗;肖春生;湯朝暉;陳學思一種聚合物微凝膠及其制備方法.CN201010130890.X,2010.
30. 莊秀麗;丁建勛;肖春生;成一龍;趙麗;湯朝暉;陳學思聚（L-谷氨酸）均聚物、無規共聚物、接枝共聚物及其制備方法.CN201010563665.5,2010.
31. 莊秀麗;丁建勛;湯朝暉;陳學思一種功能化聚酯及其制備方法.CN201010130905.2,2010.
32. 莊秀麗;丁建勛;湯朝暉;陳學思聚合物納米水凝膠及其制備方法.CN201010561226.0,2010.
33. 莊秀麗;丁建勛;高曉曄;肖春生;湯朝暉;陳學思聚合物納米水凝膠及其制備方法.CN201010563357.2,2010.
34. 莊秀麗;丁建勛;肖春生;趙長穩;湯朝暉;陳學思氯乙醇功能化聚(L-谷氨酸)均聚與無規共聚物及制法和應用.CN200910218013.5,2009.

研究方向  Researchdirection 
1、生物醫用高分子材料
2、藥物緩控釋高分子載體
3、納米藥物