湖南師范大學(xué)

鄧樂(lè)，男，理學(xué)博士，教授，博士生導(dǎo)師。

湖南師范大學(xué)生科院微生物系主任。1982年畢業(yè)于湖南師范大學(xué)獲理學(xué)士學(xué)位; 1985年獲武漢大學(xué)碩士學(xué)位。1996年獲湖南大學(xué)理學(xué)博士學(xué)位;1998 — 2000年在美國(guó)印第安那大學(xué)和加州州立大學(xué)洛杉磯分校從事博士后研究工作; 2007.7— 2007.12在英國(guó)倫敦帝國(guó)理工學(xué)院訪問(wèn)學(xué)習(xí)。2002年被湖南省確定為學(xué)科帶頭人培養(yǎng)對(duì)象。先后主持國(guó)家863計(jì)劃項(xiàng)目、國(guó)家自然科學(xué)基金項(xiàng)目等省部級(jí)課題二十多項(xiàng)。已在BIOSENS BIOELECTRON, APPL MICROBIOL BLOT, ENZYME MICROB TECH，BIORESOURCE TECHNOL等國(guó)內(nèi)外重要學(xué)術(shù)刊物上發(fā)表論文80余篇, SCI他人引用1200余次。已培養(yǎng)博士碩士50多人。 

所在學(xué)科：湖南省微生物學(xué)重點(diǎn)學(xué)科

研究及招生方向：病原菌及分子診斷技術(shù)；納米生物技術(shù); 環(huán)境微生物技術(shù)

學(xué)術(shù)兼職: 湖南省微生物學(xué)學(xué)會(huì)副理事長(zhǎng)，《生命科學(xué)研究》編委

教學(xué)：微生物學(xué)、 現(xiàn)代生物技術(shù)專題

獲獎(jiǎng):

1.鄧樂(lè), 彭智輝, 李會(huì)東 (2009) 生物功能化磁性粒子的構(gòu)建及其應(yīng)用,湖南省自然科學(xué)獎(jiǎng)二等獎(jiǎng)

2. 丁興華, 鄧樂(lè)（指導(dǎo)教師）基于碳納米管技術(shù)的快速檢測(cè)病原菌方法的研究, 湖南省優(yōu)秀碩士學(xué)位論文，2013

3.肖蕭，鄧樂(lè)（指導(dǎo)教師）高特異性免疫分子化磁性載體快速檢測(cè)病原菌的研究，湖南省優(yōu)秀碩士學(xué)位論文，2009

4.蔣軍風(fēng)，鄧樂(lè)（指導(dǎo)教師）核殼結(jié)構(gòu)水溶性量子點(diǎn)的合成與細(xì)菌檢測(cè)應(yīng)用的研究，湖南省優(yōu)秀碩士學(xué)位論文，2011

5. 雷涵, 鄧樂(lè)（指導(dǎo)教師） 微納米生物功能磁性材料的構(gòu)建及其在酶固定化中的應(yīng)用, 湖南省優(yōu)秀碩士學(xué)位論文，2005

6. 寧毅, 鄧樂(lè)（指導(dǎo)教師）高特異性碳納米生物傳感器快速檢測(cè)沙門(mén)氏菌的研究,湖南師范大學(xué)優(yōu)秀博士學(xué)位論文，2015

近五年發(fā)表主要學(xué)術(shù)論文：

1. Keyi Liu, Xing Yan, Biyao Mao, Sheng Wang, Le Deng* Aptamer-based detection of Salmonella enteritidis using double signal amplification by Klenow fragment and dual fluorescence,Microchimica Acta,183:643–649, 2016 

2. Xing Yan，Wenkai Li，Keyi Liu，Le Deng* Highly sensitive fluorescent aptasensor for Salmonella paratyphi A via DNase I-mediated cyclic signal amplification, Analytical methods,7(24), 10243-10245,  2015 

3. Yi Ning, Lijuan Cheng, Min Ling, Xinru Feng, and Le Deng*Efficient suppression of biofilm formation by a nucleicacid aptamer, FEMS Pathogens and Disease, 73(6), 1-8, 2015 

4. Zhongjie Li,Yang Song, Wenhui Zhu and Le Deng*A terminal protectionsystem for the detection of adenosine triphosphate via enzyme-assisted signal amplification, Analytical Methods, 7, 970 - 975，2015 

5. Xinru Feng, Keyi Liu, Yi Ning, Lijuan Chen and Le Deng*A Label-free Aptasensor for Rapid Detection of H1N1 Virus based onGraphene Oxide and Polymerase-aided Signal Amplification，J Nanomed Nanotechnol, 6:3，1000288，2015 

6. Wenhui Zhu, Zhongjie Li, Xinxing Liu, Le Deng*，Determination of Shigella Flexneri by a NovelFluorescent Aptasensor, Anal letters, 48(18), 2870-2881,2015 

7. Min Ling, Zhihui Peng, Lijuan Cheng, Le Deng*Rapid Fluorescent Detection of Enterotoxigenic Escherichiacoli (ETEC) K88 Based on Graphene Oxide-DependentNanoquencher and Klenow Fragment-Triggered TargetCyclic Amplification, Applied Spectroscopy, 69(10):1175-1181,2015 

8.Yang Song , Wenkai Li , Yingfen Duan , Le Deng*Nicking enzyme-assisted biosensor for Salmonella enteritidis detection based on fluorescence resonance energy transfer. Biosensors & Bioelectronics, 55, 400-404, 2014 

9. Pingdao Mao, Yi Ning, Wenkai Li, Zhihui Peng,  Le Deng*Novel strategy combining SYBR Green I with carbon nanotubes for highly sensitive detection of Salmonella typhimurium DNA. Enzyme & Microbial Tech, 54: 15-19, 2014

10.  Yinfen Duan, Yi Ning, Yang Song,  Le Deng* Fluorescent aptasensor for the determination of Salmonella typhimurium based on a graphene oxide platform. Microchim Acta,  181(5): 647-653, 2014

11.  Yi Ning, WenKai Li, YingFen Duan, Ming Yang, Le Deng* High specific DNAzyme-aptamer sensor for Salmonella paratyphi A using single-walled nanotubes based dual fluorescence-spectrophotometric methods. J. Biomolecular Screening, 19: 1099-1106, 2014

12.  Yi Ning，Yingfen Duan，Yunyi Feng，Le Deng*Label-Free Fluorescent Aptasensor based on a Graphene Oxide Self-Assembled Probe for the Determination of Adenosine Triphosphate. Analytical Letters, 47(14), 2350-2360, 2014 

13.  Zhihui Peng, Min Ling, Yi Ning, Le Deng*Rapid Fluorescent Detection of Escherichia coli K88 Based on DNA Aptamer Library as Direct and Specific Reporter Combined With Immuno-Magnetic Separation.J of Fluorescence, 24(4):1159-1168, 2014 

14.  Yi Ning, Zhong Jie Li, Yin Fen Duan, Zhi Hui Peng and Le Deng*A novel biosensor for detection of S. typhimurium carrying SSeC gene based on the secondary qurnching effect of carbon nanotubes, Nanomaterials & Molecular Nanotech, 2: 5-9, 2013

15.  Ming Yang, Zhihui Peng, Yi Ning, Le Deng *(2013) Highly Specific and Cost-Efficient Detection of Salmonella Paratyphi A Combining Aptamers with Single-Walled Carbon Nanotubes. Sensors, 13, 6865-6881

16.  Guang Li, Fushuang Li, Le Deng * Increased yield of biotransformation of exemestane with β-cyclodextrin complexation technique, Steroids, 78(11): 1148-1151, 2013

17.  Qin Zhou, Yongzhe Chen, Ming Yang, Wenkai Li, Le Deng* Enhanced bioremediation of heavy metal from effluent by sulfate-reducing bacteria with copper-iron bimetallic particles support. Bioresource Technology, 136, 120-127, 2013 (IF5.039, 1區(qū))

18.  Hui Chen, Dan Wang,Le Deng *Oligonucleotide-Based Fluorescence Probe for sensitive and selective detection of Ag(I) ions in Aqueous Solution. Water science & Technology, 85.3:444-458, 2012 

19.  Xinghua Ding, Hua Li, Le Deng* A novel homogenous detection method based on the self-assembled DNAzyme labeled DNA probes with SWNTs conjugates and its application in detecting pathogen [J] Biosensors & Bioelectronics, 26, 4596-4600，2011

20.  Dan Wang, Hui Chen, Hua Li,Le Deng*Detection of Staphylococcus aureus carrying the gene for toxic shock syndrome toxin 1 by quantum-dot-probe complexes，J of Fluorescence, 21:1525-1530, 2011 

21.  Fang Liu, Jiang Zhang, Rong Chen, Lingli Chen, Le Deng*  Highly Effective Colorimetric and Visual Detection of ATP by DNAzyme-Aptamer Sensor, Chemistry & Biodiversity, 8(2): 311-316, 2011 

22.  Hua Li, Xinghua Ding, Zhihui Peng, Le Deng*  Aptamer selection for the detection of Escherichia coli K88, Canadian journal of microbiology, 57:453-459，2011

23.  賀氣志，陳輝，鄧樂(lè)﹡ 混合硫酸鹽還原菌與Cu/Fe顆粒協(xié)同處理含鉻廢水的研究, 環(huán)境科學(xué), 32(7): 2000-2006，2011

24.  周明霞，陳勇喆，王輝，陳智，鄧樂(lè)*發(fā)光細(xì)菌PB-P3.9的鑒定與gyrB、luxA基因系統(tǒng)發(fā)育分析, 食品科學(xué), 32(15): 220-224，2011 

25.  JunFeng Jiang, ZhiHui Peng, Le Deng*Detection of Bifidobacterium Species-specific 16S rDNA Based on QD FRET Bioprobe. J of Fluorescence, 20(1): 356-369，2010 

26.Wenkai Li, Xinru Feng, Xing Yan, Keyi Liu, Le Deng*A DNA aptamer against influenza A virus: an effective inhibitor to the hemagglutinin-glycan interactions. Nucleic Acid Therapeutics, 2016 (in press) 

指導(dǎo)研究生情況：4名博士生、6名碩士生在讀；50名碩士博士畢業(yè)；

聯(lián)系方式：

Tel: 0731-88872927(O);

 Email：DengLe@Hunnu.edu.cn