北京市結核病胸部腫瘤研究所

免疫學專業

褚洪遷，男，北京大學醫學博士，國家納米科學中心博士后，現任北京市結核病胸部腫瘤研究所副研究員，碩士研究生導師。

研究方向為基于復合納米材料的疾病診療作用研究。主要是結合腫瘤臨床治療的困境設計合成多功能復合納米材料，實現時空可控的精準抗腫瘤免疫。先后在Nat Commun、Angew Chem Int Ed Engl、Environ Pollut、Sci Total Environ等國際刊物上發表高水平論文10余篇，參與發表中英文文章30余篇。主持局級以上科研課題3項，其中包括國家自然科學基金1項(在研)，北京市自然科學基金1項(在研)，北京市醫院管理中心培育項目1項(在研)，同時參與多項局級以上課題。與天津大學、中央民族大學、國家納米科學中心一直保持深度合作，整合多平臺實現人才有效培養。現為中國研究型醫院協會醫工轉化與健康產業融合分會委員。

論文發表：

1. Jianhong Ge#, Hongqian Chu#, Qianqian Xiao, Weidong Hao, Jing Shang, Tong Zhu, Zhaogang Sun, Xuetao Wei*. BC and 1,4NQ-BC up-regulate the cytokines and enhance IL-33 expression in LPS pretreatment of human bronchial epithelial cells. Environ. Pollut. 2021, 273:116452.

2. Hongqian Chu#, Xi Tao#, Zhaogang Sun, Weidong Hao, Xuetao Wei*. Galactooligosaccharides protects against DSS-induced murine colitis through regulating intestinal flora and inhibiting NF-κB pathway. Life Sci. 2020, 242: 117220.

3. Hongqian Chu, Jian Zhao, Yongsheng Mi, Zhenghan Di, Lele Li*. NIR-light-mediated spatially selective triggering of anti-tumor immunity via upconversion nanoparticle-based immunodevices. Nat. Commun. 2019, 10(1): 2839.

4. Hongqian Chu#, Jian Zhao#, Yongsheng Mi, Yuliang Zhao, Lele Li*. Near-infrared light-initiated hybridization chain reaction for spatially and temporally resolved signal amplification. Angew. Chem. Int. Ed. Engl. 2019, 58(42): 14877-14881.

5. Zhiyuan Cheng#, Hongqian Chu#, Siqi Wang, Yao Huang, Xiaohong Hou, Qi Zhang, Wenjuan Zhou, Lixia Jia, Qinghe Meng, Lanqin Shang, Yiming Song, Weidong Hao, Xuetao Wei*. TAK1 knock-down in macrophage alleviate lung inflammation induced by black carbon and aged black carbon. Environ. Pollut. 2019, 253: 507-515.

6. Hongqian Chu, Weidong Hao, Zhiyuan Cheng, Yao Huang, Siqi Wang, Jing Shang, Xiaohong Hou, Qinghe Meng, Qi Zhang, Lixia Jia, Wenjuan Zhou, Pengmin Wang, Guang Jia, Tong Zhu, Xuetao Wei*. Black Carbon Particles and Ozone-Oxidized Black Carbon Particles Induced Lung Damage in Mice Through an interleukin-33 Dependent Pathway. Sci. Total Environ. 2018, 644: 217-228.

7. Hongqian Chu, Jing Shang, Ming Jin, Yueyue Chen, Yuan Li, Yao Pan, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Qian Li, Guang Jia, Tong Zhu, Xuetao Wei*, Weidong Hao*. Comaprison of lung damage in mice exposed to black carbon particles and 1,4-naphthoquinone coated black carbon particles. Sci. Total Environ. 2017. 580:572-581.

8. Hongqian Chu, Jing Shang, Ming Jin, Qian Li, Yueyue Chen, Hongpeng Huang, Yuan Li, Yao Pan, Xi Tao, Zhiyuan Cheng, Qinghe Meng, Guang Jia, Tong Zhu, Xuetao Wei*, Weidong Hao*. Comaprison of lung damage in mice exposed to black carbon particles and ozone-oxidized black carbon particles. Sci. Total Environ. 2016. 573: 303-312.

9. Hongqian Chu#, Qiuqiong Tang#, Hongpeng Huang, Weidong Hao, Xuetao Wei*. Grape-seed proanthocyanidins inhibit the lipopolysaccharide-induced inflammatory mediator expression in RAW264.7 macrophages by suppressing MAPK and NF-Κb signal pathways. Environ. Toxicol. Pharmacol, 2016. 41: 159-166.

10. Hongqian Chu#, Jun Li#, Hongpeng Huang, Weidong Hao, Liping Duan*, Xuetao Wei*. Protective effects of tranilast on oxazolone-induced rat colitis through a mast cell-dependent pathway. Dig. Liver Dis. 2016. 48: 162-171.