蘭州大學(xué)

主講本科生《細(xì)胞生物學(xué)》課程，研究生《植物細(xì)胞信號轉(zhuǎn)導(dǎo)專題》、《博士生前沿進(jìn)展講座——細(xì)胞生物學(xué)專業(yè)》等課程。已經(jīng)畢業(yè)博士研究生7位、碩士研究生50位，指導(dǎo)60余名本科生畢業(yè)論文。畢業(yè)研究生去向有國外著名大學(xué)博士后，國內(nèi)重要科研、教學(xué)以及企業(yè)等單位的科研、教學(xué)和管理人員。

研究生主要招生方向：

植物細(xì)胞信號轉(zhuǎn)導(dǎo)、植物激素的分子機(jī)理等。

發(fā)表論文及專著

Guo XL, Qin QQ, Yan J, Niu YL, Huang BY, Guan LP, Li Y, Ren DT, Li J,Hou SW*. 2015. TYPE-ONE PROTEIN PHOSPHATASE4 regulates pavement cell interdigitation by modulating PIN-FORMED1 polarity and trafficking in Arabidopsis. Plant Physiology, 167: 1058–1075

Han B, Chen L, Wang J, Wu ZL, Yan LF, Hou SW*. 2015. Constitutive Expresser of Pathogenesis Related Protein 1 is required for pavement cell morphogenesis in Arabidopsis. PLOS One, Accepted article.

Yang JX, Yan LF, Song YJ, Chai CC, Song LL, Guan LP,Hou SW*. 2015. New roles for the Arabidopsis TAO1 gene besides disease resistance. Russ J Plant Physl, 62, 542–550

Zhou WQ, Wu ZL, Zhang YC, Wu DL, Liu D, Wang YC, Gao QX, Dang BR, Li WJ, Hou SW*. 2015. Stable inheritance of excellent agricultural traits induced by 12C6+ heavy-ions in lentil (Lens culinaris Medik.). Czech J. Genet. Plant Breed, 51, 29–35

Wang W, Zhang J, Qin QQ, Yue J, Huang BY, Xu XF, Yan LF, Hou SW*. 2014. The six conserved serine/threonine sites of REPRESSOR OF ga1-3 protein 1 are important for its functionality and stability in gibberellin signaling in Arabidopsis. Planta, 240: 763–779

Qin QQ, Wang W, Guo XL, Yue J, Huang Y, Xu XF, Li J, Hou SW*. 2014. Arabidopsis DELLA protein degradation is controlled by a type-one protein phosphatase, TOPP4. PLOS Genetics, 10(7): e1004464. doi:10.1371/journal.pgen.1004464. http://www.plosgenetics.org/doi/pgen.1004464

Yan LF, Cheng X, Jia RL, Qin QQ, Guan LP, Du H, Hou SW*. 2014. New phenotypic characteristics of three tmm alleles in Arabidopsis thaliana. Plant Cell Reports, 33: 719–731

Hu ZH,Xu F, Guan LP,Qian PP,Liu YQ, Zhang HF, Huang Y, Hou SW*. 2014. The tetratricopeptide repeat-containing protein Slow Green1 is required for chloroplast development in Arabidopsis. Journal of Experimental Botany, 65: 1111–1123

Qian PP, Han B, Forestier E, Hu ZH, Gao N, Lu WW, Schaller H, Li J, Hou SW*. 2013. Sterols are required for cell fate commitment and maintenance of the stomatal lineage in Arabidopsis. The Plant Journal, 74:1029–1044

Guo XL, Lu WW, Ma YR, Qin QQ, Hou SW*. 2013. The BIG gene is required for auxin-mediated organ growth in Arabidopsis. Planta, 237: 1135-1147

Luo L, Zhou WQ, Liu P, Li CX, Hou SW*. 2012. The development of stomata and other epidermal cells on the rice leaves. Biologia Plantarum, 56(3): 521-527

Qian PP, Hou SW*, Guo GQ. 2009. Molecular mechanisms controlling pavement cell shape in Arabidopsis leaves. Plant Cell Reports, 28: 1147-1157

Wu DL, Hou SW*, Qian PP, Sun LD, Zhang YC, Li WJ. 2009. Flower color chimera and abnormal leaf mutants induced by 12C6+ heavy ions in Salvia splendens Ker- Gawl. Scientia Horticulturae, 121: 462-467

Sun LD, Hou SW*, Wu DL, Zhang YC. 2008. Rapid clonal propagation of Zygophyllum xanthoxylon (Bunge) Maxim., an endangered desert forage species. In Vitro Cellular Development Biology - Plant. 44: 396-400

Dodd AN, Jakobsen MK, Baker AJ, Tezerow A, Hou SW, Laplaze L, Barrot L, Poethig RS, Haseloff J, Webb AR. 2006. Time of day modulates low-temperature Ca2+ signals in Arabidopsis. The Plant Journal, 48:962-973

He WT, Hou SW*, Wang CY. 2006. Callus induction and high-frequency plant regeneration from hypocotyl and cotyledon explants of Arctium lappa L. In Vitro Cellular and Development Biology-Plant, 42（5）: 411-414

He WT, Hou SW*, Wang CY. 2006. An efficient in vitro method for mass propagation of Potentilla potaninii Wolf. In Vitro Cellular and Development Biology-Plant, 42（5）: 415-417

Hou SW*, Jia JF. 2005. In vitro regeneration of Perilla frutescens from hypocotyl and cotyledon explants. Biologia Plantarum, 49: 129-132

Hou SW*, Jia JF. 2004. High frequency regeneration from Astragalus melilotoides hypocotyl and stem explants via somatic embryogenesis and organogenesis. Plant Cell Tissue and Organ Culture, 2004, 79: 95-100

Hou SW*, Jia JF. Plant regeneration from protoplasts isolated from embryogenic calli of the forage legume Astragalus melilotoides Pall. Plant Cell Reports, 2004, 22: 741-46

研究方向

1、植物激素作用分子機(jī)理。研究生長素轉(zhuǎn)運(yùn)、赤霉素信號通路的磷酸化與去磷酸化調(diào)控，包括赤霉素信號轉(zhuǎn)導(dǎo)中DELLA蛋白穩(wěn)定性的磷酸化與去磷酸化修飾調(diào)控機(jī)理，PINs 蛋白的去磷酸化調(diào)控等。關(guān)于蛋白磷酸酶 TOPP4 通過 DELLA 去磷酸化正調(diào)控 GA 信號轉(zhuǎn)導(dǎo)的成果發(fā)表在國際著名遺傳學(xué)學(xué)術(shù)期刊PLOS Genetics; TOPP4去磷酸化PIN1調(diào)控其在細(xì)胞內(nèi)外的極性分布，進(jìn)而控制細(xì)胞形態(tài)建成的成果發(fā)表在國際著名植物學(xué)期刊Plant Physiology。

2、植物氣孔和表皮細(xì)胞發(fā)育與形態(tài)建成調(diào)控機(jī)理。分布在植物表皮的氣孔和扁平細(xì)胞，是研究細(xì)胞發(fā)育和功能的絕好模式體系。我們以擬南芥、水稻為材料，通過正向和反向遺傳學(xué)構(gòu)建和篩選突變體，揭示表皮細(xì)胞的發(fā)育圖式和形態(tài)建成的內(nèi)在調(diào)控因子和信號轉(zhuǎn)導(dǎo)機(jī)制，闡明其分子機(jī)理。我們通過自己建立的研究體系，已經(jīng)克隆到多個(gè)參與氣孔及表皮細(xì)胞形態(tài)建成的基因，發(fā)現(xiàn)其同時(shí)也參與了一些植物激素的合成與信號轉(zhuǎn)導(dǎo)過程。植物甾醇調(diào)控氣孔圖式發(fā)育的成果發(fā)表在著名植物學(xué)期刊The Plant Journal。

項(xiàng)目成果

主持6項(xiàng)國家自然科學(xué)基金，其中1項(xiàng)為重大研究計(jì)劃培育項(xiàng)目；參加2項(xiàng)科技部“973”計(jì)劃項(xiàng)目、3項(xiàng)農(nóng)業(yè)部轉(zhuǎn)基因?qū)ｍ?xiàng)；主持2項(xiàng)甘肅省自然科學(xué)基金、1項(xiàng)甘肅省生物技術(shù)專項(xiàng)等。

榮譽(yù)、獲獎(jiǎng)

1、教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃（2006年）；

2、甘肅省自然科學(xué)二等獎(jiǎng)（2008年）；

3、陜西省科學(xué)技術(shù)獎(jiǎng)二等獎(jiǎng)（2006年）；

4、蘭州大學(xué)隆基中青年教師教學(xué)骨干獎(jiǎng)（2009年）；

5、蘭州大學(xué)“三育人”先進(jìn)個(gè)人（2007年）；

6、蘭州大學(xué)第二屆“教學(xué)新秀獎(jiǎng)”（2000年）。

社會工作

《植物學(xué)報(bào)》第七屆編輯委員會責(zé)任編委；中國細(xì)胞生物學(xué)學(xué)會第九屆理事，中國細(xì)胞生物學(xué)會植物器官發(fā)生分委員會委員、細(xì)胞生物學(xué)教學(xué)與普及工作委員會委員；中國植物學(xué)會外事處副主任；甘肅省植物學(xué)會理事；蘭州大學(xué)生命科學(xué)學(xué)院副院長，蘭州大學(xué)生命科學(xué)學(xué)院學(xué)術(shù)委員會副主任委員、學(xué)位評定分委員會副主席等社會兼職。