華東理工大學(xué)

華東理工大學(xué)生物工程學(xué)院生物工程研究生導(dǎo)師謝靜莉介紹如下：

食品科學(xué)專業(yè)：碩士生導(dǎo)師

生物工程專業(yè)：碩士生導(dǎo)師

生物工程領(lǐng)域：工程碩士導(dǎo)師

謝靜莉，女，工學(xué)博士，副研究員，華東理工大學(xué)生物工程學(xué)院。

現(xiàn)任生物反應(yīng)器工程國(guó)家重點(diǎn)實(shí)驗(yàn)室常務(wù)副主任，曾任華東理工大學(xué)生物工程學(xué)院食品科學(xué)與工程系副主任、常務(wù)副主任。先后作為課題組長(zhǎng)或負(fù)責(zé)人承擔(dān)科技部863計(jì)劃、國(guó)家自然科學(xué)基金青年基金項(xiàng)目、上海市科技攻關(guān)項(xiàng)目子課題，科技部973計(jì)劃項(xiàng)目子課題等多項(xiàng)國(guó)家及省部級(jí)課題，并與雀巢上海研發(fā)有限公司、美國(guó)派拉蒙農(nóng)場(chǎng)有限公司、上海漢康豆類(lèi)食品有限公司等多家國(guó)內(nèi)外企業(yè)進(jìn)行合作。發(fā)表學(xué)術(shù)論文53篇，其中以通訊/第一作者身份發(fā)表SCI論文30篇，授權(quán)專利7項(xiàng)。

主要經(jīng)歷：

2005年4月至今：華東理工大學(xué)生物工程學(xué)院食品科學(xué)與工程系教師，生物反應(yīng)器工程國(guó)家重點(diǎn)實(shí)驗(yàn)室固定人員

2003年10月-2005年3月于西班牙：CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS（最高科學(xué)理事會(huì)）CENTRO DE INVESTIGACIONES BIOLOGICAS （生物研究中心），分子生物學(xué)博士后研究工作

2003年6月畢業(yè)于華東理工大學(xué)生物工程學(xué)院生物反應(yīng)器工程國(guó)家重點(diǎn)實(shí)驗(yàn)室，工學(xué)博士

2000年7月畢業(yè)于華東理工大學(xué)生物工程學(xué)院生物反應(yīng)器工程國(guó)家重點(diǎn)實(shí)驗(yàn)室，工學(xué)碩士

1996年7月畢業(yè)于華東理工大學(xué)能源化工系，工學(xué)學(xué)士

主要研究方向：

食品生物技術(shù)：基于功能基因組學(xué)的乳酸菌益生功能研究與天然活性物質(zhì)代謝途徑研究；基于結(jié)構(gòu)生物學(xué)的食品酶學(xué)研究與酶制劑開(kāi)發(fā)；具有益生和促進(jìn)健康作用的發(fā)酵食品開(kāi)發(fā)技術(shù)。

功能性食品：基于生物信息學(xué)與生物計(jì)算學(xué)的食源性活性肽靶向酶解與構(gòu)效關(guān)系研究；活性肽類(lèi)功能食品開(kāi)發(fā)技術(shù)。

主講課程：

食品科學(xué)碩士點(diǎn)專業(yè)主干課程：食品生物技術(shù)與工程

食品科學(xué)與工程系本科課程：專業(yè)英語(yǔ)、分子營(yíng)養(yǎng)學(xué)

論文及專利（2014-2017）：

論文
1.Guo M#, Chen X#, Wu J, Zhang L, Huang W, Yuan Y, Fang M, Xie J*, Wei D. Angiotensin I-converting enzyme inhibitory peptides from Sipuncula (Phascolosoma esculenta). Process Biochemistry. 2017, DOI 10.1016/j.procbio.2017.08.009

2.Zhu Q, Chen X, Wu J,Zhou Y, Qian Y, Fang M, Xie J*, Wei D. Dipeptidyl peptidase IV Inhibitory peptides from Chlorella vulgaris: In silico gastrointestinal hydrolysis and molecular mechanism. European Food Research and Technology. 2017, DOI 10.1007/s00217-017-2879-1

3.Zhang J, Zhao L, Gao B, Wei W, Wang H, Xie J*. Protopectinase production by Paenibacillus polymyxa Z6 and its application in pectin extraction from apple pomace. Journal of Food Processing and Preservation. 2017(1): e13367

4.Yang Y, Sun J, Wu J, Zhang L, Du L, Matsukawa S, Xie J*, Wei D. Characterization of a novel α-L-arabinofuranosidase from Ruminococcus albus 7 and rational design for its thermostability. Journal of Agricultural and Food Chemistry. 2016 Dec, 64 (40): 7546–7554

5.Lang C, Yang R, Yang Y, Zhao L, Gao B, Wei W, Wang H, Matsukawa S, Xie J*, Wei D. An acid-adapted endo-a-1,5-L-arabinanase for pectin releasing. Applied Biochemistry and Biotechnology. 2016 Nov, 180 (5): 900-916

6.Zhu Q#, Qian Y#, Yang Y, Wu W, Xie J*, Wei D. Effects of carbonyl iron powder on iron deficiency anemia and its subchronic toxicity. Journal of Food and Drug Analysis. 2016 Oct, 24 (4): 746-753

7.Du L, Brenner T, Xie J, Matsukawa S*. A study on phase separation behavior in kappa/iota carrageenan mixtures by micro DSC, rheological measurements and simulating water and cations migration between phases. Food Hydrocolloids. 2016, 55:81-88 

8.Zhao L, Lin J, Wang H, Xie J, Wei DZ*. Development of a two-step process for production of 3-hydroxypropionic acid from glycerol using Klebsiella pneumoniae and Gluconobacter oxydans. Bioprocess and Biosystems Engineering. 2015, 38 (12):2487-2495

9.Wang Y, Wang Y, Lang C, Wei D, Xu P, Xie J*. Genome Sequence of Lactobacillus curieae CCTCC M 2011381T, a Novel Producer of Gamma-aminobutyric Acid. Genome Announcements. 2015, 3(3):e00552-15

10.Yang Y, Zhang L, Guo M, Sun J, Matsukawa S, Xie J*, Wei D. Novel α-L-arabinofuranosidase from Cellulomonas fimi ATCC 484 and its substrate-specificity analysis with the aid of computer. Journal of Agricultural and Food chemistry. 2015, 63(14):3725-3733

11.Chen M, Lei X, Chen C, Zhang S, Xie J*, Wei D. Cloning, overexpression and characterization of a highly active endoinulinase gene from Aspergillus fumigatus CL1 for production of inulo-oligosaccharides. Applied Biochemistry and Biotechnology. 2015, 175(2):1153-1167

12.Fan J, Cui Y, Zhou Y, Wan M, Wang W, Xie J, Li Y*. The effect of nutrition pattern alteration on Chlorella pyrenoidosa growth, lipid biosynthesis-related gene transcription. Bioresource Technology. 2014, 164(1):214-220.

13.Liu Y, Zhang L, Guo M, Wu H, Xie J*, Wei D. Virtual screening for angiotensin I-converting enzyme inhibitory peptide from Phascolosoma esculenta. Bioresources and Bioprocessing. 2014, 1:17

14.Wang S, Yang Y, Zhang J, Sun J, Matsukawa S, Xie J*, Wei D. Characterization of abnZ2 (yxiA1) and abnZ3 (yxiA3) in Paenibacillus polymyxa, encoding two novel endo-1,5-α-L-arabinanases, AbnZ2 (YxiA1) and AbnZ3 (YxiA3). Bioresources and Bioprocessing. 2014, 1: 14

15.Wang S, Yang Y, Yang R, Zhang J, Chen M, Matsukawa S, Xie J*, Wei D. Cloning and characterization of a cold-adapted endo-1,5-α-L-arabinanase from Paenibacillus polymyxa and rational design for acidic applicability. Journal of Agricultural and Food chemistry. 2014, 62(33): 8460-8469

16.Wu H, Liu Y, Guo M, Xie J*, Jiang X*. A Virtual screening method for inhibitory peptides of angiotensin I converting enzyme. Journal of Food Science. 2014, 79(9): 1635-1642

17.WuY, LiuY, GuoM, LiP, DuL, FangM, WuH,XieJ*, WeiD. Nutritional composition and antihypertensive activity on spontaneously hypertensive rats of sipuncula Phascolosoma esculenta. Food and Function. 2014, 5 (9): 2317-2323

18.Li P, Jia J, Fang M, Zhang L, Guo M, Xie J*, Xia Y, Zhou L, Wei D. In vitro and in vivo ACE inhibitory of pistachio hydrolysates and in silico mechanism of identified peptide binding with ACE.Process Biochemistry. 2014, 49(5): 898-904

19.Li P, Jia J, Zhang D, Xie J*, Xu X, Wei D. In vitro and in vivo antioxidant activities of flavonoidfrom celery (Apium graveolens L. var. dulce). Food and Function. 2014, 5:50-56

20.Chen J, Yang R, Chen M, Wang S, Li P, Xia Y, Zhou L, Xie J*, Wei D. Production optimization and expression of pectin releasing enzyme from Aspergillus oryzae PO. Carbohydrate Polymers. 2014, 101:89-95

21.Zhou P, Zhang Y, Wang P, Xie J*, Ye Q.Butanol production from glycerol by recombinant Escherichia coli. Annuals of Microbiology. 2014, 64:219-227

授權(quán)專利

1、謝靜莉，張龍，曹小飛，高允盛，趙丹，許學(xué)書(shū). 一種含豆乳的奶酪及其制備方法. ZL 200810202514.X

2、張 晞，許學(xué)書(shū)，謝靜莉，余東輝，夏月蘭. 封閉式固體發(fā)酵反應(yīng)裝置. ZL 200910047129.7

3、謝靜莉，張龍，許學(xué)書(shū)，高允盛，曹小飛，林炯.一種拉絲型混合干酪的制作方法及獲得的混合干酪. ZL 200910051486.0

4、謝靜莉，李晴輝，魏東芝. 一種涂抹型大豆干酪及其制作方法. ZL 201110358380.2

5、謝靜莉，雷曉，孫貴朋，魏東芝. 一種食源性乳酸菌及其應(yīng)用. ZL 201210044449.9

6、謝靜莉，方明，李鵬，杜磊，吳燕玲，魏東芝. 降血壓多肽. ZL 2013101240332

7、謝靜莉，方明，張旭晟，鄧高靜，吳燕玲，王波，束雯婷，李瑩，杜磊，李鵬. 蓮子用于制備ACE抑制劑的應(yīng)用. ZL 201210137731.1

聯(lián)系方式：

電話：64251803 (O), 64252563 (Lab)

E-mail: jlxie@ecust.edu.cn