北京化工大學(xué)化學(xué)工程與技術(shù)專業(yè)研究生導(dǎo)師介紹：羅施中

羅施中，教授，博士生導(dǎo)師。

1999年本科畢業(yè)于清華大學(xué)化學(xué)系，同年免試攻讀清華大學(xué)直博生，2004年獲清華大學(xué)化學(xué)博士學(xué)位，并榮獲清華大學(xué)優(yōu)秀博士學(xué)位論文獎。2004年至2008年，在美國德克薩斯大學(xué)休斯頓醫(yī)學(xué)科學(xué)中心生物化學(xué)和分子生物學(xué)系從事博士后科研工作。2008年9月以北京化學(xué)大學(xué)高層次引進(jìn)人才的方式進(jìn)入北京化工大學(xué)生命學(xué)院工作，主要從事生物化工和化學(xué)生物學(xué)的相關(guān)研究工作，包括生物自組裝體系的研究；基于生物加工過程中的相關(guān)代謝調(diào)控、代謝組學(xué)和蛋白質(zhì)組學(xué)研究；食品安全和環(huán)境安全檢測；計算化學(xué)和分子模擬研究。

作為項目負(fù)責(zé)人先后承擔(dān)國家自然科學(xué)基金項目，科技部863項目，北京市科技新星和教育部博士點基金項目，作為承擔(dān)單位的負(fù)責(zé)人承擔(dān)973重大研究計劃項目和國家自然科學(xué)基金重點項目各1項。發(fā)表了包括國外高水平期刊Blood，JBC，JMB和Biophysical Journal在內(nèi)的SCI論文二十多篇，參編專著一本。榮獲2013年北京市科技新星，2013年北京市科學(xué)技術(shù)獎（三等獎），2012年北京化工大學(xué)第十二屆青年主講教師，2008年第十屆中國國際多肽大會Young Peptide Scientist Award等獎勵。

主要發(fā)表文章如下：

 

1)          Zhiling Zhu, Mengxue Feng, Limin Zuo, Zhentai Zhu, Fengwei Wang, Long Chen, Jinghua Lib, Guangzhi Shan*, Shi-Zhong Luo*(通訊作者)  An aptamer based surface plasmon resonance biosensor for the detection of2 ochratoxin A in wine and peanut oil. Biosensors and Bioelectronics Accepted (IF=6.0，Top雜志)；

2)          Fude Sun, Lei Zhang, Jianhua Yan, Lida Xu, Decai Fang and Shi-Zhong Luo*(通訊作者)  The synthesis and photolysis mechanisms of 8-nitroquinoline-based photolabile caging groups for carboxylic acid.  J. Phys. Org. Chem. Accepted (SCI)

3)          Peng Wei, Lida Xu,  Cheng-Dong Li, Fu-De Sun, Long Chen, Tianwei Tan, Shi-Zhong Luo*(通訊作者)  Molecular Dynamic Simulation of the Self-Assembly DAP12-NKG2C Activating Immunoreceptor Complex.  PLOS One, 9(8), e1005560 (IF=3.7，Top雜志)

4)          Peng Wei, Bo-Kai Zheng,Peng-Ru Guo, Toru Kawakami, Shi-Zhong Luo*(通訊作者) The Association of Polar Residues in the DAP12 homodimer: TOXCAT and Molecular Dynamics Simulation Studies Biophysical Journal, 2013 Apr 2;104(7):1435-44. (IF=4.3，Top雜志)；

5)          Yunfei Sun, Long Chen, Fude Sun, Xibo Tian, Shi-Zhong Luo* New amphiphilic N-phosphoryl oligopeptides designed for gene delivery. International Journal of Pharmaceutics 468 (2014) 83–90 (IF=3.6)；

6)          Lin Chang，Pengyu Bi，Yanan Liu，Yinglin Mu，F(xiàn)engquan Nie，Shizhong Luo， and Yun Wei*, Simultaneous Analysis of Trace Polymer Additives in Plastic Beverage Packaging by Solvent Sublation Followed by High-Performance Liquid Chromatography J. Agric. Food Chem. dx.doi.org/10.1021/jf401748a (IF=2.9，Top雜志)

7)          Lida Xu  Ting-Ting Hu Shi-Zhong Luo*(通訊作者) Leucine Zipper Motif Drives the Transmembrane Domain Dimerization of E-cadherin International Journal of Peptide Research and Therapeutics, Accepted. (SCI)

8)          Fengxiang Qie, Guoxin Zhang, Jianxuan Hou, Xiaoming Sun, Shi-zhong Luo*(通訊作者), Tianwei Tan* Nucleic acid from beans extracted by ethanediamine magnetic particles Journal of Food Science and Technology (SCI)

9)          Xi-Rui Zhou, Rui, Ge, Shi-Zhong Luo* (通訊作者) Self-assembly of pH and calcium dual-responsive peptide-amphiphilic hydrogel. Journal of Peptide Science. 2013 19(12): 737-44. (IF=1.8)

10)       Xiao-Li Lv, Shi-Zhong Luo*(通訊作者) A fluorescence chemosensor based on peptidase for detecting  nickel(II) with high selectivity and high sensitivity, Analytical and Bioanalytical Chemistry, 2012, 402(9):2999-3002; (IF=3.84，二區(qū)雜志)；

11)       Fengxiang Qie, Guoxin Zhang, Jianxuan Hou, Xiaoming Sun, Shi-Zhong Luo*(通訊作者), Tianwei Tan*(通訊作者), Talanta, 2012, 93,166-171; (IF=3.7，二區(qū)雜志)；

12)       Xiao-Li Lv, Yun Wei, Shi-Zhong Luo*(通訊作者) A “Turn-On” Fluorescent Chemosensor Based on Peptidase for Detecting Copper (II), Analytical Science,2012, 28(8), 749. (SCI) 獲得當(dāng)期的Hot Article Award

13)       Peng Wei, Xin Liu, Miaohui Hu, Limin Zuo, Rui Wang, Shi-Zhong Luo*（通訊作者）The dimerization interface of the glycoprotein Ibb transmembrane domain corresponds to polar residues within a leucine zipper motif, Protein Science, 2011,20(11):1814-1823; (IF=3.0, 二區(qū)雜志)；

14)       Ting-Ting Hu and Shi-Zhong Luo*，“Phosphorylation-Induced Structural Changes in the C-Terminus of c-Fos Detected by CD and NMR” International Journal of Peptide Research and Therapeutics, 2011,17(1):19-30. (SCI)

15)       Yan-Jing Kang, Li-Min Zuo, Shi-Zhong Luo*, “Hydrogen-Bonding Interactions Induced by Phosphorylation Influence the Local Conformation of Phosphopeptides”, International Journal of Peptide Research and Therapeutics, 2010，16(2):87-93. (SCI)

16)       Xi Mo, Nam X. Nguyen, Fi-tjen Mu, Shi-Zhong Luo, Huizhou Fan, Robert K. Andrews, Michael C. Berndt, Renhao Li. “Trans-membrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ib[alpha]”. Journal of Biology Chemistry, 2010, 285: 32096-32104. (IF=5.3，Top雜志)

17)       Shi-Zhong Luo, Renhao Li. “Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex”, Journal of Molecular Biology, 2008, 382, 448-457. (IF=4.9，Top雜志)

18)       Shi-Zhong Luo, Xi Mo, Vahid Afshar-Kharghan, Sankaranarayanan Srinivasan José A.López, and Renhao Li. “Glycoprotein Ib? forms disulfides with two glycoprotein Ib? subunits in the resting platelet”. Blood, 2007, 109, 603-609. (IF=10.1，Top雜志) Featured in a commentary in Blood, 2007, 109, 393-394.

19)       Shi-Zhong Luo, Xi Mo, José A.López, and Renhao Li. “Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex”. Journal of Thrombosis and Haemostasis, 2007, 5,2494-2502. (IF=5.9，二區(qū)雜志)

20)       Xi Mo, Shi-Zhong Luo, Yuandong Peng, Adam D Munday, Carol Sun, Michael C. Berndt, José A. López, Jing-fei Dong, and Renhao Li. “Removing the covalent links between GPIba and GPIbb hampers binding of von Willebrand Factor to GPIb-IX Complex in CHO cells”, Accepted by Journal of Thrombosis and Haemostasis. (IF=5.9，二區(qū)雜志)

21)       Xi Mo, Shi-Zhong Luo, José A. López, and Renhao Li. “Juxtamembrane basic residues in glycoprotein Ibb cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex”, FEBS Letters, 2008, 582, 3270-3274. (IF=3.4)

22)       Shi-Zhong Luo, Yan-Mei Li,.Wei Qiang, Yu-Fen Zhao, Hiroshi Abe, Tadashi Nemoto, Xu-Rong Qin, and Hiroshi Nakanishi. “Detection of Specific Non-Covalent Interaction of Peptide with DNA by MALDI-TOF”. Journal of The American Society for Mass Spectrometry, 2004,15,28-31(IF=3.6).

23)       Shi-Zhong Luo, Yan-Mei Li, Yan-Ling Niu, Yi Chen, Yu-Yang Jiang, Jing Chen and Yu-Fen Zhao. “Characterization of an Electrospray Ionization Mass Spectrometry for N-Diisopropyloxyphosphory Dipeptide Methyl Esters”. European Journal of Mass Spectrometry, 2005,11,107-118, (SCI)

24)  Shi-Zhong Luo, Yan-Mei Li, Zhong-Zhou Chen, Hiroshi Abe, Li-Ping Cui, Hiroshi Nakanishi, Xu-Rong Qin and Yu-Fen Zhao. “Synthesis and matrix assisted laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry study of phosphopeptide”. Letters in peptide science, 2003,10,57-62. (SCI)