江南大學(xué)生物工程學(xué)院碩士生導(dǎo)師介紹：蔡宇杰

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性別：男
出生年月：1973.12
職稱、職務(wù)：教授
電話：0510-85327725
電子郵箱：yjcai@jiangnan.edu.cn
【研究領(lǐng)域】

主要從事生物化學(xué)及下游工程等方面交叉學(xué)科的研究。
主要研發(fā)天然功能性產(chǎn)物：竹紅菌素、蟲草素、EPA、DHA、ARA及功能性酶等。
已產(chǎn)業(yè)化產(chǎn)品：模擬移動床色譜、工業(yè)制備色譜系統(tǒng)
【科研項目】

主持項目：
集成化通用型智能模擬移動床色譜裝置開發(fā)與產(chǎn)業(yè)化,江蘇省科技攻關(guān)重點項目,2006.4-2007.12
生物、醫(yī)藥用模擬移動床色譜分離純化裝置關(guān)鍵技術(shù)開發(fā)及產(chǎn)業(yè)化,江蘇省科技成果轉(zhuǎn)化重大專項項目，BA2007077,2007.10-2010.9
竹黃菌全細(xì)胞催化合成竹紅菌素關(guān)鍵技術(shù)研究,科技部科技人員服務(wù)企業(yè)項目，2009GJ10038,2009.5-2010.5,
基于蛋白質(zhì)組差異分析方法的竹紅菌素代謝途徑關(guān)鍵催化過程研究，國家自然科學(xué)基金，21045007，2011.1-2011.12,
廣譜抗癌新藥竹紅菌素全細(xì)胞合成及純化關(guān)鍵技術(shù)研究,江蘇省科技創(chuàng)新與成果轉(zhuǎn)化（重大科技支撐與自主創(chuàng)新）專項引導(dǎo)資金B(yǎng)Y2010117,2010.7-2012.12
中央高校基本科研業(yè)務(wù)費專項資金資助JUSRP21120，2011.1-2012.12
竹紅菌素合成代謝過程中關(guān)鍵酶快速分析平臺的構(gòu)建及應(yīng)用研究，國家自然科學(xué)基金，21275066,2013.1-2016.12
參與項目：
降血壓活性肽的基因表達(dá)和分離技術(shù)的研究(863探索導(dǎo)向類)科技部2007.10-2010.9
【科研成果及獎勵】
2008年中國石油與化學(xué)工業(yè)聯(lián)合會科技進(jìn)步三等獎（排名第一）
2012年中國石油與化學(xué)工業(yè)聯(lián)合會科技進(jìn)步一等獎（排名第一）
2012年教育部科技進(jìn)步二等獎（排名第一）
2012年江蘇省科技進(jìn)步三等獎（排名第三）
【主要論著】
YangY,DingY,LiaoX,CaiY:PurificationandcharacterizationofanewlaccasefromShiraiasp.SUPER-H168.ProcessBiochem2013,48(2):351-357.
LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD,LiZ:Efficiencyoflaccaseproductionina65-Lair-liftreactorforpotentialgreenindustrialandenvironmentalapplication.In:JournalofCleanerProduction.vol.39;2013:154-160.
LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD:PurificationandCharacterisationofaNovelThermalStableLaccasefromPycnoporusSp.Sybc-L3anditsuseinDyeDecolorisation.Biology&Environment:ProceedingsoftheRoyalIrishAcademy2013,113(1):1-13.
DingY,CaiY:ConformationaldynamicsofxylanaseafromStreptomyceslividans:ImplicationsforTIM-barrelenzymethermostability.Biopolymers2013,99(9):594-604.
ZengX,CaiY,LiaoX,ZengX,LuoS,ZhangD:AnthraquinonedyeassistedthedecolorizationofazodyesbyanovelTrametestrogiilaccase.ProcessBiochem2012,47(1):160-163.
LiuJ,CaiY,LiaoX,HuangQ,HaoZ,HuM,ZhangD:SimultaneouslaccaseproductionandcolorremovalbyculturingfungusPycnoporussp.SYBC-L3inatextilewastewatereffluentsupplementedwithalignocellulosicwastePhragmitesaustralis.BullEnvironContamToxicol2012,89(2):269-273.
HuMM,CaiYJ,LiaoXR,HaoZK,LiuJY:DevelopmentofanHPLCmethodtoanalyzeandprepareelsinochromeCandhypocrellinAinthesubmergedfermentationbrothofShiriasp.SUPER-H168.BiomedChromatogr2012,26(6):737-742.
HaoZ,CaiY,LiaoX,ZhangX,FangZ,ZhangD:OptimizationofnutritionfactorsonchitinaseproductionfromanewlyisolatedChitiolyticbactermeiyuanensisSYBC-H1.BrazJMicrobiol2012,43:177-186.
DingY,CaiY,HanY,ZhaoB,ZhuL:Applicationofprincipalcomponentanalysistodeterminethekeystructuralfeaturescontributingtoironsuperoxidedismutasethermostability.Biopolymers2012,97(11):864-872.
DingY,CaiY,HanY,ZhaoB:Comparisonofthestructuralbasisforthermalstabilitybetweenarchaealandbacterialproteins.Extremophiles2012,16(1):67-78.
ZengXK,CaiYJ,LiaoXR,LiW,ZhangDB:DecolorizationofsyntheticdyesbycrudelaccasefromanewlyisolatedTrametestrogiistraincultivatedonsolidagro-industrialresidue.JHazardMater2011,187(1-3):517-525.
ZengHW,CaiYJ,LiaoXR,ZhangF,ZhangDB:AninducedstrategyofregulationofcarbonmetabolismandstatisticaloptimizationforproductionenhancementofcatalasebySerratiamarcescensSYBC08fromsludgewithhydrogenperoxide.AsianJournalofChemistry2011,23(4):1488-1492.
ZengHW,CaiYJ,LiaoXR,ZhangF,ZhangDB:Production,characterization,cloningandsequenceanalysisofamonofunctionalcatalasefromSerratiamarcescensSYBC08.JBasicMicrobiol2011,51(2):205-214.
SuYJ,SunJ,RaoS,CaiYJ,YangYJ:PhotodynamicantimicrobialactivityofhypocrellinA.JPhotochemPhotobiolB2011,103(1):29-34.
SuY,SiS,QiaoL,CaiY,XuZ,YangY:TheeffectofahypocrellinAenricheddietoneggyolkqualityandhypocrellinAdistributionsinthemeatoflayinghens.EurFoodResTechnol2011,232(6):935-940.
LiGY,CaiYJ,LiaoXR,YinJ:Anovelnonionicsurfactant-andsolvent-stablealkalineserineproteasefromSerratiasp.SYBCHwithduckweedasnitrogensource:production,purification,characteristicsandapplication.JIndMicrobiolBiotechnol2011,38(7):845-853.
LiGY,CaiYJ,LiaoXR,YinJ:Enzymaticsynthesisofsucroseoctaacetateusinganovelalkalineprotease.BiotechnolLett2011,33(3):607-610.
HaoZK,CaiYJ,LiaoXR,LiangXH,LiuJ,FangZ,HuMM,ZhangDB:ChitinolyticbactermeiyuanensisSYBC-H1(T),Gen.Nov.,sp.Nov.,aChitin-DegradingBacteriumIsolatedFromSoil.CurrMicrobiol2011,62(6):1732-1738.
CaiYJ,LiaoXR,LiangXH,DingYR,SunJ,ZhangDB:InductionofhypocrellinproductionbyTritonX-100undersubmergedfermentationwithShiraiasp.SUPER-H168.NBiotechnol2011,28(6):588-592.
CaiY,LiuS,LiaoX,DingY,SunJ,ZhangD:PurificationandpartialcharacterizationofantifreezeproteinsfromleavesofLigustrumlucidumAit.FoodandBioproductsProcessing2011,89(2):98-102.
ZengHW,CaiYJ,LiaoXR,QianSL,ZhangF,ZhangDB:Optimizationofcatalaseproductionandpurificationandcharacterizationofanovelcold-adaptedCat-2frommesophilicbacteriumSerratiamarcescensSYBC-01.AnnMicrobiol2010,60(4):701-708.
YuanBH,CaiYJ,LiaoXR,YunLH,ZhangF,ZhangDB:Isolationandidentificationofacold-adaptedlipaseproducingstrainfromdecayedseedsofGinkgobilobaL.andcharacterizationofthelipase.AfrJBiotechnol2010,9(18):2661-2667.
WangZX,CaiYJ,LiaoXR,ZhangF,ZhangD,LiZL:ProductionandCharacterizationofaNovelLaccasewithColdAdaptationandHighThermalStabilityfromanIsolatedFungus.ApplBiochemBiotechnol2010,162(1):280-294.
WangZX,CaiYJ,LiaoXR,TaoGJ,LiYY,ZhangF,ZhangDB:PurificationandcharacterizationoftwothermostablelaccaseswithhighcoldadaptedcharacteristicsfromPycnoporusspSYBC-L1.ProcessBiochem2010,45(10):1720-1729.
SunJ,ZhaoJ,WuXJ,FangW,CaiYJ,XuWB:ParameterestimationforchaoticsystemswithaDriftParticleSwarmOptimizationmethod.PhysicsLettersA2010,374(28):2816-2822.
SuYJ,RaoSQ,CaiYJ,YangYJ:PreparationandcharacterizationoftheinclusioncomplexofhypocrellinAwithhydroxypropyl-beta-cyclodextrin.EurFoodResTechnol2010,231(5):781-788.
CaiYJ,WuHG,LiaoXR,DingYR,SunJ,ZhangDB:PurificationandCharacterizationofNovelManganesePeroxidasefromRhizoctoniasp.SYBC-M3.BiotechnolBioprocessEng2010,15(6):1016-1021.
CaiYJ,WeiZY,LiaoXR,DingYR,SunJ:CharacterizationofthreeextracellularpolysaccharidesfromShiraiaspSuper-H168undersubmergedfermentation.CarbohydrPolym2010,82(1):34-38.
CaiYJ,LiangXH,LiaoXR,DingYR,SunJ,LiXH:High-YieldHypocrellinAProductioninSolid-StateFermentationbyShiraiaspSUPER-H168.ApplBiochemBiotechnol2010,160(8):2275-2286.
CaiY,SunJ,WangJ,DingY,LiaoX,XuW:QPSOBT:Onecodonusageoptimizationsoftwareforproteinheterologousexpression.JournalofBioinformaticsandSequenceAnalysis2010,2(2):25-29.
SuYJ,YinXY,RaoSQ,CaiYJ,ReuhsB,YangYJ:NaturalcolourantfromShiraiabambusicola:stabilityandantimicrobialactivityofhypocrellinextract.InternationalJournalofFoodScienceandTechnology2009,44(12):2531-2537.
32.LiangXH,CaiYJ,LiaoXR,WuK,WangL,ZhangDB,MengQ:IsolationandidentificationofanewhypocrellinA-producingstrainShiraiaspSUPER-H168.MicrobiolRes2009,164(1):9-17.
33.DingDW,DingYR,LiLN,CaiYJ,XuWB:Structuralandfunctionalanalysisofgiantstrongcomponentofbacillusthuringiensismetabolicnetwork.BrazJMicrobiol2009,40(2):411-416.
34.CaiYJ,WangL,LiaoXR,DingYR,SunJ:Purificationandpartialcharacterizationoftwonewcold-adaptedlipasesfrommesophilicGeotrichumsp.SYBCWU-3.ProcessBiochem2009,44(7):786-790.
35.DingDW,DingYR,LuKZ,ChenSW,CaiYJ,XuWB:RobustnessinB-thuringiensisMetabolicNetwork.RivistaDiBiologia-BiologyForum2008,101(2):265-277.
36.DingDW,DingYR,CaiYJ,ChenSW,XuWB:Exploringpoly-beta-hydroxybutyratemetabolismthroughnetwork-basedextremepathwayanalysis.RivistaDiBiologia-BiologyForum2008,101(1):67-79.
37.CaiYJ,SunJ,WangJ,DingYR,TianN,LiaoXR,XuWB:OptimizingthecodonusageofsyntheticgenewithQPSOalgorithm.JTheorBiol2008,254(1):123-127.
38.CaiYJ,DingYR,TaoGJ,LiaoXR:Productionof1,5-dihydroxy-3-methoxy-7-methylanthracene-9,10-dionebysubmergedcultureofShiraiabambusicola.JMicrobiolBiotechnol2008,18(2):322-327.
39.DingYR,CaiYJ,ZhangGX,XuWB:Theinfluenceofdipeptidecompositiononproteinthermostability.FEBSLett2004,569(1-3):284-288.