蘭州大學藥學院碩士研究生導師信息介紹：薛偉華

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姓名：薛偉華(男)

職稱職務：副教授

電子郵箱xuewh@lzu.edu.cn

1、學習與工作經歷

2003年9月--2006年7月在南京大學生物化學專業學習，獲博士學位

2006年7月-2007年7月在加拿大阿爾伯特大學訪問學習

2007年6月--2009年8月在海中國科學院上海有機化學研究所工作

2009年9月-現在在蘭州大學工作

2、教學工作與成果

講授分析化學和物理化學

3、科研項目與成果

1.WeihuaXue,HuajiaDiao,XiChen,JiangningChenandJunfengZhang.Anefficientvectorforgenedelivery:α,β-poly(3-dimethylaminopropyl-D,L-aspartamide),EuropeanJournalofPharmaceuticsandBiopharmaceutics2007(66)327-333.

2.WeihuaXue,XiaoyunCheng,JianFan,HuajiaDiao,ChunmingWang,YiLuo,JiangningChenandJunfengZhang.Anovelstereoselectivesynthesisof1,2-trans-thioaldoses,TetrahedronLetter2007(48)6092-6095.

3.WeihuaXue,JiansongSunandBiaoYu.Anefficientrouteto2-amnio-β-galactosidesand-glucosidesviastereoselectiveMichaelAdditionof2-nitrogalactal.JournaloforganicChemistry2010(74)5079-5082.

4.WeihuaXue,*LifenZhang.AnImprovedandAlternativeMethodforthePreparationofPer(6-bromo-6-deoxy)cyclodextrins.Synthesis,2011,3612–3614

5.WeihuaXue,*LifenZhang.ANovelProtocolfortheRegioselectiveBrominationofPrimaryAlcoholsinUnprotectedCarbohydratesorGlycosides.ChinesejournalofChemistry,2012(30)1429-1432

6.WeihuaXue,*LifenZhang.B(C6F5)3asaHighlyEffectiveCatalystforthePhosphorylTransferReaction.ChinesejournalofChemistry,2012(30)1997-1800

7.XiaofengLiu,SenCheng,XiaoleiWang,WeihuaXue*.Aconvenientprocedurefortheformationofper(6-deoxyl-6-halo)cyclodextrinsusingthecombinationoftetraethylammoniumhalidewith[Et2NSF3]BF4.Synthesis,2013,45,3103-3105.

8.XiaolongYuan,SenCheng,YanbinShi,WeihuaXue*.Photocatalyticsynthesisofglycosylbromide.Synthesis,2014,331-335

9.LanYu,WeihuaXue,CuiLei,HongyuLi.Useofhydroxypropyl-β-cyclodextrin/polyethyleneglycol400,modifiedFe3O4nanoparticlesforcongoredremoval.Internationaljournalbiologicalmacromolecules.2014,64,233-239.

10.DaboPan,WeihuaXue,XiaotingWang,JingjingGuo,HuanxiangLiu,XiaojunYao.MolecularMechanismoftheEnhancedVirulenceof2009PandemicInfluenzaA(H1N1)VirusfromD222GMutationintheHemagglutinin:AMolecularModelingStudy.JournalofMolecularModeling,2012,18,4355-4366.

11.XiaoyunCheng,WeihuaXue,HuajiaDiaoandJunfengZhang.AntitumoractivityandtoxicologicalpropertiesofDoxorubicinconjugatedtoα,β-poly[(2-hydroxyethyl)-L-aspartamide]administratedintraperitoneallyinmice.AnticancerDrug2010(21)362-372.

4、研究與招生方向

糖化學和糖生物學