湖南師范大學(xué)生命科學(xué)學(xué)院生物化學(xué)與分子生物學(xué)研究生導(dǎo)師：陳平

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湖南師范大學(xué)生命科學(xué)學(xué)院生物化學(xué)與分子生物學(xué)研究生導(dǎo)師陳平介紹如下：

陳平,二級教授，生物化學(xué)博士。 1962年11月生， 1983年畢業(yè)于湖南大學(xué)化學(xué)化工學(xué)院分析化學(xué)專業(yè),1988年獲湖南師范大學(xué)生命科學(xué)學(xué)院生物化學(xué)與分子生物學(xué)碩士學(xué)位， 2005 年獲生物化學(xué)與分子生物學(xué)博士學(xué)位。 2001 年曾作為訪問學(xué)者在美國佛羅里達(dá)大學(xué)分子細(xì)胞生物化學(xué)系作訪問研究。近年來主要從事蛋白質(zhì)化學(xué)與蛋白質(zhì)組學(xué)的研究。主持了國家 973 項目子課題“膜蛋白以及膜蛋白復(fù)合體的分離鑒定新方法新技術(shù)”、國家 973 前期項目“與血管生成啟動相關(guān)的質(zhì)膜蛋白質(zhì)組研究”、國家自然科學(xué)基金項目“肝臟再生過程中血竇內(nèi)皮細(xì)胞功能蛋白質(zhì)分析”、“肝再生過程中質(zhì)膜微區(qū)蛋白質(zhì)及復(fù)合物動態(tài)變化研究”、“肝再生過程中肝血竇內(nèi)皮細(xì)胞動態(tài)調(diào)控的信號途徑及機(jī)制研究”、“多肽探針研究Nav1.7調(diào)節(jié)前列腺癌PC3細(xì)胞轉(zhuǎn)移的分子機(jī)制 ” ，以及湖南省科技廳重點項目“細(xì)胞膜蛋白質(zhì)組研究方法發(fā)展及其在神經(jīng)系統(tǒng)細(xì)胞質(zhì)膜蛋白質(zhì)組研究中的應(yīng)用”的研究；并作為主要骨干研究人員參與并完成了國家科技攻關(guān)計劃“人類健康肝臟蛋白質(zhì)組表達(dá)譜以及國家 973 項目“重要疾病的蛋白質(zhì)組學(xué)研究”等研究工作；曾獲 2007 年及 2003 年湖南省科技廳科技進(jìn)步獎一等獎和 1999 年國家教育部科技進(jìn)步獎三等獎以及 1 項國家專利（專利號 為： ZL 2004 1 0023089 X ）。在“ Journal of Neurochemistry ”、“ Journal of Proteome Research ” 等雜志上已發(fā)表相關(guān)論文8 0 余篇，參編著作三部。

近五年主持的各類國家科技計劃項目情況:

近年來以通訊作者或第一作者發(fā)表的主要研究論文

1.Jiang M, Qi L, Liu P, Wang Z, Duan Z, Wang Y, Liu Z, Chen P*,. Selective enrichment and desalting of hydrophilic peptides using graphene oxide. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Aug 1; 1027:149-157.

2.Ge L, Jiang M, Duan D, Wang Z, Qi L, Teng X, Zhao Z, Wang L, Zhuo Y, Chen P*, He X, Lu M.  Secretome of Olfactory Mucosa Mesenchymal Stem Cell, a Multiple Potential Stem Cell.  Stem Cells Int. 2016:1243659.

3.Yu J, Lin S, Wang M, Liang L, Zou Z, Zhou X, Wang M, Chen P*, Wang Y. Metastasis suppressor 1 regulates neurite outgrowth in primary neuron cultures.Neuroscience. 2016, 333:123-131 

4.Cheng Zhang, Jinyan Li, Xinhong Guo, Baode Zhu, Wenjun Xiao, Ping Wang, Miao Jiang, Shuai Hu, Xiutao Lu, Zhuang He, Ping Chen*. LecRK-VII.1, a Lectin Receptor-Like Kinase, Mediates the Regulation of Salt Stress and Jasmonic Acid Response in Arabidopsis. Journal of Plant Growth Regulation. 2016,12

5.Li J, Gao J, Jiang M, Chen J, Liu Z, Chen P*, Liang S. Rat liver sinusoidal surface N-linked glycoproteomic analysis by affinity enrichment and mass spectrometric identification. Biochemistry (Mosc). 2015 Mar;80(3):260-75

6.Zhang W, Long J, Zhang C, Cai N, Liu Z, Wang Y, Wang X, Chen P*, Liang S.  A method combining SPITC and 18O labeling for simultaneous protein identification and relative quantification. J.Mass.Spectrom. 2014,49(5):400-408 

7.Wang L, Jiang M, Duan D, Zhao Z, Ge L, Teng X, Liu B, Liu B, Chen P*, Lu M.Hyperthermia-conditioned OECs serum-free-conditioned medium induce NSC differentiation into neuron more efficiently by the upregulation of HIF-1 alpha and binding activity.Transplantation. 2014,97(12):1225-1232 

8.Rui Cao, Ke Chen, Qin Song, Yi Zang, Jia Li, Xianchun Wang, Ping Chen*and Songping Liang. Quantitative Proteomic Analysis of Membrane Proteins Involved in Astroglial Differentiation of Neural Stem Cells by SILAC Labeling Coupled with LC–MS/MS. J.Proteome Res., 2012, 11 (2)：829–838     

9.Shi N, Tian C, Liang X, Jiang P, Liang L, Zhou L, Shu Y. Chen P*，Wang Y. Proteome analysis of actin filament a ssociated proteins in the postnatal rat cerebellum. Neuroscience.2012，227: 90-101.

10.Chunliang Xie, Nvying Liu, Jia Long, Cheng Tang, Jianglin Li, Linju Huo, Xianchun Wang, Ping Chen*, Songping Liang.  Blue Native/SDS-PAGE Combined with iTRAQ Analysis Reveals Advanced Glycation Endproducts-Induced Changes of Synaptosome Proteins in C57 BL/6 Mice.  Electrophoresis.2011, 32: 2194–2205   

11.Liu Y, Teng X, Yang X, Song Q, Lu R, Xiong J, Liu B, Zeng N, Zeng Y, Long J, Cao R, Lin Y, He Q, Chen P*, Lu M, Liang S.  Shotgun proteomics and network analysis between plasma membrane and extracellular matrix proteins from rat olfactory ensheathing cells. Cell transplantation.  2010,19(2):133-146.     

12.Cao R, Liu Y, Chen P*, Lv R, Song Q, Sheng T, He Q, Wang Y, Wang X, Liang S. Improvement of hydrophobic integral membrane protein identification by mild performic acid oxidation-assisted digestion.  Anal Biochem. 2010 ,15;407(2):196-204. 

13.Xuanwen Li, Li Xiong, Chunliang Xie, Jia Cao, Huobao Deng, Yong Lin, Rui Cao, Jianglin Li, Ping Chen* , Songping Liang.  Proteomics analysis of plasma membrane from liver sinusoidal endothelial cells after partial hepatectomy by an improved two-dimensional electrophoresis. Molecular and Cellular Biochemistry2010，344（1-2）： 137-150.   

14.Li Xuanwen, Xie Chunliang, Jin Qihui, Liu Minhjun, He Quanyuan, Cao Rri, Lin Ying, Li Jianglin, Li Yan, Chen Ping*, Liang Songping. Proteomic Screen for Multiprotein Complexes in Synaptic Plasma Membrane from Rat Hippocampus by Blue Native Gel Electrophoresis and Tandem Mass Spectrometry， Journal of Proteome Research，2009，8：3475-3486   

15.Chen Ping, Zhang Lijun, Li Xuanwen, Wang Xie, Cao Rui, Liu Zhen,Cao Rui, Xiong Jixian, Peng Xia, Wei Yingjuan, Wang Xianchun, and Liang Songping.Evaluation of strategy for analyzing mouse liver plasma membrane proteome.Science in China Series C:Life Sciences. 2007,50(6)：731-738                       

16.Chen Ping, Li Xuanwen, Sun Yalan, Liu Zhen,Cao Rui, He Quanyuan, Wang Meichi, Xiong Jixian, Xie Jinyun, Wang Xianchun, and Liang Songping. Proteomic analysis of rat hippocampus plasma membrane:characterization of potential neuronal-specific plasma membraneproteins. Journal OfNeurochemistry. 2006,98：1126-1140 

17.Chen Ping, Nie Song，Wang Xiangchun, Liang Songping. De nove sequencing of tryptic peptides sulfonated by 4-sulfophenyl isothiocyanate for unambiguous protein identification using post-source decay matrix-assisted laser desorption/ionization mass spectrometry.  Rapid Commun. Mass Spectrom，2004,18:191-198.     

18.陳平參編著作《CLINICALRESEARCHAND TREATMENT APPROACHES TO AFFECTIVE DISORDERS》（英文）, 歐洲INTECH出版社，2012年