河北大學(xué)化學(xué)與環(huán)境科學(xué)學(xué)院研究生導(dǎo)師：王克讓

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河北大學(xué)化學(xué)與環(huán)境科學(xué)學(xué)院研究生導(dǎo)師王克讓介紹如下：

一、個(gè)人簡(jiǎn)介

王克讓，男，1979年，博士，教授，博導(dǎo)，讀博士期間師從南開大學(xué)劉育教授(2006~2009年)，讀碩士期間師從鄭州大學(xué)張雁冰教授(2003~2006年)，2009年到河北大學(xué)工作，主要從事功能超分子納米組裝體構(gòu)筑和識(shí)別研究、基于生物效應(yīng)的熒光傳感研究和抗腫瘤化合物的合成及作用機(jī)制研究等。目前主持國(guó)

家自然科學(xué)基金和河北省自然科學(xué)基金等8項(xiàng)。2016年獲河北省杰出青年基金。2016年入選河北省“三三三人才工程”三層次人選。在Adv. Funct. Mater., Chem. Commun., ACS Macro Lett., Chem. Eur. J.和Biosens. Bioelectron.等上發(fā)表論文三十幾篇，授權(quán)發(fā)明專利6項(xiàng)。

聯(lián)系方式：kerangwang@163.com

二、主講課程及研究方向

1. 主講課程：有機(jī)化學(xué)

2. 研究方向：超分子化學(xué)，化學(xué)生物學(xué)

三、代表性論文

1) Chun-Miao Zhao, Ke-Rang Wang*, Chong Wang, Xu He, Xiao-Liu Li*. Cooling-induced NIR emission enhancement and targeting fluorescence imaging of bi-perylene monoimide and glycodendrimer conjugates. ACS Macro Lett., 2019, 8, 381-386.

2) Jiu-Kai Xiong, Ke-Rang Wang,* Kai-Xin Wang, Tian-Lei Han, Hong-Yu Zhu, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescent enhancement sensing of Cadmium (II) ion based on a perylene bisimide derivative. Sens. Actuators B Chem., 2019, 297, 126802.

3) Juan-Juan Li, Ke-Rang Wang*, Ren-Feng Li, Jian-Xing Yang, Min Li, Hong-Xin Zhang, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis, self-assembly behaviours and multivalent glycosidase inhibition effect of deoxynojirimycin modified perylene bisimide derivatives. J. Mater. Chem. B, 2019, 7, 1270-1275.

4) Min Li, Ke-Rang Wang*, Jian-Xing Yang, Ya-Tong Peng, Yi-Xuan Liu, Hong-Xin Zhang, Xiao-Liu Li*. Supramolecular azasugar clusters based on an amphiphilic fatty-acid-deoxynojirimycin derivative as multivalent glycosidase inhibitors. J. Mater. Chem. B, 2019, 7, 1379-1383.

5) Xiao Chen, Ya-Nan Wang, Rui-Xue Rong, Chun-Miao Zhao, Xiao-Liu Li*, Ke-Rang Wang*. Synthesis, thermos-responsive behavior of cyclodextrin modified bi-perylene monoimide derivative. Dyes Pigments, 2019, 160, 779-786.

6) Qi Xu, Jia-Li Wang, Ya-Li Luo, Juan-Juan Li, Ke-Rang Wang*, Xiao-Liu Li*. Host-guest interactions and controllable capture and release of proteins based on cationic perylene bisimides. Chem. Commun., 2017, 53, 2241-2244.

7) Guo-Jing Cao, Rui-Xue Rong, Ya-Nan Wang, Qi Xu, Ke-Rang Wang*, Xiao-Liu Li*. Synthesis and Photodynamic therapy of Mono-mannose Modified Perylene Bisimide Bridged Permethyl-b-CDs. Dyes Pigments, 2017, 136, 569-576.

8) Ke-Rang Wang*, Zi-Bo Yang, Xiao-Liu Li*. High excimer-state emission of perylene bisimides and its recognition of latent fingerprints. Chem. Eur. J., 2015, 21, 5680-5684. (Frontispieces)

9) Ke-Rang Wang*, Dan Han, Guo-Jing Cao, Xiao-Liu Li*.Synthesis and predetermine supramoecular chirality of carbohydrates functionalized perylene bisimide derivatives. Chem. Asian J., 2015, 10, 1204-1214.

10)Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis of biocompatible glycodendrimer based on fluorescent perylene bisimides and its bioimaging. Macromol. Rapid. Commun., 2014, 35, 727-734.

11) Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescence turn-on sensing of protei based on mannose funtioalized perylee bsmides and its fluorescence imaging. Biosens. Bioelectron., 2014, 58, 27-32.

12) Ke-Rang Wang, Yue-Qng Wan, Hong-Wei An, Jin-Cao Zhang, Xiao-Liu Li*. A triazatruxen-based glycoclusters as a fluorescent sensor for Concanavalin A. Chm. Eur. J., 2013, 19, 2903-2909.

13) Ke-Rang Wang, Hong-Wei An, Ling, Wu, Jin-Chao Zhang, Xiao-Liu Li*. Ciral self-assembly of lactose functionalized perylene bisimides as multivalent glycocluster. Chem. Commun., 2012, 48, 5644-5646.

14) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Yu Liu*. Excitonic coupling interations in the self-assemby of perylene-bridged bis(beta-cyclodextrin)s and porphyrin. Chem. Commun., 2012, 48, 3644-3646.

15) Ke-Rang Wang*, Hong-Wei An, Yue-Qing Wang, Jin-Chao Zhang, Xiao-Liu Li*. Multivalent glycoclusters constructed by chial self-assembly of mannose functionalized perylene bisimide. Org. Bimol. Chem., 2013, 11, 1007-1012.

16) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Zhan-Hu Sun, Yu Liu*. Molecuar aggregtion behavior of perylene-bridged bis(beta-cyclodextrin)s and its electron interactions upon selective binding with aromatic guests. J. Phys. Chem. B, 2010, 114, 101-106.

17) Yu Liu*, Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang. Supramolecular assembly of peryene bisimide with beta-cyclodextrin grafts as solid-state fluorescent sensor for vapor detection. Adv. Funct. Mater., 2009, 19, 2230-2235.

四、科研項(xiàng)目

1)國(guó)家自然科學(xué)基金(面上項(xiàng)目)：苝-環(huán)糊精-糖類超分子多效價(jià)糖基組裝體的構(gòu)筑、識(shí)別和靶向給藥研究，項(xiàng)目編號(hào)：21372059，起止時(shí)間：2014-2017，主持，結(jié)題。

2) 河北省自然科學(xué)基金(杰出青年基金)：苝酰亞胺-野尻毒素超分子多效價(jià)糖苷酶抑制劑的研究，項(xiàng)目編號(hào): B2016201254，起止時(shí)間：2016/01-2018/12，主持，結(jié)題.

3)國(guó)家自然科學(xué)基金(青年基金)：苝-糖類衍生物超分子多效價(jià)組裝體的構(gòu)筑及與凝集素作用研究，項(xiàng)目編號(hào)：21002020，起止時(shí)間：2011-2013，主持，結(jié)題。

4)河北省自然科學(xué)基金：苝-糖類衍生物超分子多效價(jià)組裝體的構(gòu)筑及與凝集素的識(shí)別研究，項(xiàng)目編號(hào)：B2011201052，起止時(shí)間：2011-2013， 主持，結(jié)題。

5)河北省自然科學(xué)基金：多胺連接萘酰亞胺類和二氯乙酰胺類抗腫瘤化合物的合成及性質(zhì)研究，項(xiàng)目編號(hào)：B2012201041，起止時(shí)間：2012-2014，主持，結(jié)題。

6)河北省高等學(xué)校科學(xué)技術(shù)研究項(xiàng)目(優(yōu)秀青年基金)：苝-環(huán)糊精-糖類多效價(jià)糖基組裝體的構(gòu)筑和性質(zhì)研究，項(xiàng)目編號(hào)：YQ2013006，起止時(shí)間：2013-2015，主持，結(jié)題。