西南大學(xué)研究生化學(xué)化工學(xué)院導(dǎo)師信息：向云

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西南大學(xué)化學(xué)化工學(xué)院碩士研究生導(dǎo)師向云信息介紹：

向云 （Yun Xiang）, 博士

教授，博士生導(dǎo)師

郵件地址：yunatswu@swu.edu.cn

通訊地址：重慶市北碚區(qū)西南大學(xué)化學(xué)化工學(xué)院 400715

教育經(jīng)歷：

2005. 1~2008. 10 美國(guó)亞利桑那州立大學(xué) 分析化學(xué) 博士學(xué)位

2003. 8~2004. 12 美國(guó)新墨西哥州立大學(xué) 分析化學(xué) 博士研究生

2000. 9~2003. 7  四川大學(xué)化學(xué)學(xué)院 工業(yè)催化 碩士學(xué)位

1995. 9~1999. 7  四川大學(xué)化學(xué)學(xué)院 儀器分析 學(xué)士學(xué)位

工作經(jīng)歷：

2011. 7~至今 西南大學(xué)化學(xué)化工學(xué)院 教授

2008. 12~2011. 6 西南大學(xué)化學(xué)化工學(xué)院 特聘教授

2005. 1~2008. 10 美國(guó)亞利桑那州立大學(xué) Research Assistant

2003. 8~2004. 12 美國(guó)新墨西哥州立大學(xué) Teaching Assistant

研究方向：

生物傳感器（Biosensors）、生物電分析化學(xué)（Bio-electroanalysis）、納米生物技術(shù)（Nanobiotechnology）

研究?jī)?nèi)容：

1.基于新型納米材料分析信號(hào)放大的疾病標(biāo)志物高靈敏電化學(xué)生物傳感

2.生物分子的可視化分析

3.DNA自組裝及DNA納米結(jié)構(gòu)在生物分析中的應(yīng)用

主持課題：

1.國(guó)家自然科學(xué)基金青年－面上連續(xù)資助項(xiàng)目（2013–2016）

2.教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃資助項(xiàng)目（2013–2015）

3.國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目（2010）

4.留學(xué)回國(guó)人員科技活動(dòng)資助項(xiàng)目（2012-2014）

5.中國(guó)博士后科學(xué)基金特別資助項(xiàng)目（2010-2012）

6.重慶市自然科學(xué)基金一般項(xiàng)目（2009-2012）

7.中央高校基本科研業(yè)務(wù)費(fèi)專項(xiàng)資金重點(diǎn)項(xiàng)目（2009-2011）、團(tuán)隊(duì)項(xiàng)目（2012-2014）

8.西南大學(xué)博士基金（含引進(jìn)人才計(jì)劃）項(xiàng)目（2009）

代表論文：

1.Wenjiao Zhou,Xue Gong, Yun Xiang,* RuoYuan, YaqinChai, Target-triggered quadratic amplification for label-free and sensitive visual detection of cytokines based on hairpin aptamer DNAzyme probes, Analytical Chemistry, 2014, 86, 953–958.

2.Ying Chen, Mengli Yang, Yun Xiang,* Ruo Yuan,* Yaqin Chai, Binding-induced autonomous disassembly of aptamer-DNAzyme supersandwich nanostructures for sensitive electrochemiluminescence turn-on detection of Ochratoxin A, Nanoscale, 2014, 6, 1099–1104.

3.Qiong Wang,Cuiyun Yang, Yun Xiang,* RuoYuan, Yaqin Chai, Dual amplified and ultrasensitive electrochemical detection of mutant DNA biomarkers based on nuclease-assisted target recycling and rolling circle amplifications, Biosensors & Bioelectronics, 2014, 55, 266–271.

4.Wenjiao Zhou,Xue Gong, Yun Xiang,* RuoYuan, Yaqin Chai, Quadratic recycling amplification for label-free and sensitive visual detection of HIV DNA, Biosensors & Bioelectronics, 2014, 55, 220–224.

5.Jin Xu, Qiong Wang, Yun Xiang,* Ruo Yuan, Yaqin Chai, Cascade signal amplification for ultrasensitive electrochemical DNA detection, Analyst, 2014, 139, 128–132.

6.Wenjiao Zhou, Jiao Su, Yaqin Chai, Ruo Yuan, Yun Xiang,* Naked eye detection of trace cancer biomarkers based on biobarcode and enzyme-assisted DNA recycling hybrid amplifications, Biosensors & Bioelectronics, 2014, 53, 494–498.

7.Yunying Xu, Jin Xu, Yun Xiang,* Ruo Yuan, Yaqin Chai, Target-induced structure switching of hairpin aptamers for label-free and sensitive fluorescent detection of ATP via exonuclease-catalyzed target recycling amplification, Biosensors & Bioelectronics, 2014, 51, 293–296.

8.Jiao Su, Wenjiao Zhou, Yun Xiang,* Ruo Yuan, Yaqin Chai, Target-induced charge reduction of aptamers for visual detection of lysozyme based on positively charged gold nanoparticles, Chemical Communications, 2013, 49, 7659–7661.

9.Mengli Yang, Ying Chen, Yun Xiang,* Ruo Yuan, Yaqin Chai, In situ energy transfer quenching of quantum dot electrochemiluminescence for sensitive detection of cancer biomarkers, Biosensors & Bioelectronics, 2013, 50, 393–398.

10.Ying Chen, Mengli Yang, Yun Xiang,* Ruo Yuan,* Yaqin Chai, Ligase chain reaction amplification for sensitive electrochemiluminescent detection of single nucleotide polymorphisms, Analytica Chimica Acta, 2013, 796, 1–6.

11.Qiong Wang, Bingying Jiang, Jiaqing Xie, Yun Xiang,* Ruo Yuan, Yaqin Chai, Coupling of background reduction with rolling circle amplification for highly sensitive protein detection via terminal protection of small molecule-linked DNA, Analyst, 2013, 138, 5751–5756.

12.Ying Chen, Qiong Wang, Jin Xu, Yun Xiang,* Ruo Yuan,* Yaqin Chai, A new hybrid signal amplification strategy for ultrasensitive electrochemical detection of DNA based on enzyme-assisted target recycling and DNA supersandwich assemblies, Chemical Communications, 2013, 49, 2052–2054.

13.Jiao Su, Jin Xu, Ying Chen, Yun Xiang,* Ruo Yuan, Yaqin Chai, Sensitive detection of copper(II) by a commercial glucometer using click chemistry, Biosensors & Bioelectronics, 2013, 45,219–222.

14.Qiong Wang, Bingying Jiang, Jin Xu, Jiaqin Xie, Yun Xiang,* Ruo Yuan, Yaqin Chai, Amplified terminal protection assay of small molecule/protein interactions via a highly characteristic solid-state Ag/AgCl process, Biosensors & Bioelectronics, 2013, 43, 19–24.

15.Ling Kong, Jin Xu, Yunying Xu, Yun Xiang,* Ruo Yuan, Yaqin Chai, A universal and label-free aptasensor for fluorescent detection of ATP and thrombin based on SYBR Green I dye, Biosensors & Bioelectronics, 2013, 42, 193–197.

16.Ying Chen, Jin Xu, Jiao Su, Yun Xiang,* Ruo Yuan,* Yaqin Chai, In situ hybridization chain reaction amplification for universal and highly sensitive electrochemiluminescent detection of DNA, Analytical Chemistry, 2012, 84, 7750–7755.

17.Jin Xu, Bingying Jiang, Jiaqing Xie, Yun Xiang,* Ruo Yuan, Yaqin Chai, Sensitive point-of-care monitoring of HIV related DNA sequences with a personal glucometer, Chemical Communications, 2012, 48, 10733–10735.

18.Jiao Su, Jin Xu, Ying Chen, Yun Xiang,* Ruo Yuan, Yaqin Chai, Personal glucose sensor for point-of-care early cancer diagnosis, Chemical Communications, 2012, 48, 6909–6911.

19.Jin Xu, Bingying Jiang, Jiao Su, Yun Xiang,* Ruo Yuan, Yaqin Chai, Background current reduction and biobarcode amplification for label-free, highly sensitive electrochemical detection of pathogenic DNA, Chemical Communications, 2012, 48, 3309–3311.

20.Bingying Jiang, Min Wang, Ying Chen, Jiaqing Xie, Yun Xiang,* Highly sensitive electrochemical detection of cocaine on graphene/AuNP modified electrode via catalytic redox-recycling amplification, Biosensors & Bioelectronics, 2012, 32, 305–308.

21.Haixia Zhang, Bingying Jiang, Yun Xiang,* Yaqin Chai, Ruo Yuan,* Label-free and amplified electrochemical detection of cytokine based onhairpin aptamer and catalytic DNAzyme, Analyst, 2012, 137, 1020–1023.

22.Qiong Wang, Jiao Su, Jin Xu, Yun Xiang,* Ruo Yuan, Yaqin Chai, Dual amplified, sensitive electrochemical detection of pathogenic sequencesbased on biobarcode labels and functional graphene modified electrode, Sensors and Actuators, B 2012, 163, 267–271.

23.Yun Xiang, Mingyi Xie, Ralph Bash, Julian J. L. Chen, Joseph Wang,* Ultrasensitive label-free aptamer-based electronic detection, Angewandte Chemie-International Edition, 2007, 46, 9054–9056.

24.Yun Xiang,* Haixia Zhang, Bingying Jiang, Yaqin Chai, Ruo Yuan,* Quantum dot layer-by-layer assemblies as signal amplification labels for ultrasensitive electronic detection of uropathogens, Analytical Chemistry, 2011, 83, 4302–4306.

25.Ying Chen, Bingying Jiang, Yun Xiang,* Yaqin Chai, Ruo Yuan,* Target recycling amplification for sensitive and label-free impedimetric genosensing based on hairpin DNA and graphene/Au nanocomposites Chemical Communications, 2011, 47, 12798–12800.

26.Jiao Su, Haijie Zhang, Bingying Jiang, Huzhi Zheng, Yaqin Chai, Ruo Yuan, Yun Xiang,* Dual signal amplification for highly sensitive electrochemical detection of uropathogens via enzyme-based catalytic target recycling, Biosensors & Bioelectronics, 2011, 29, 184–188.

27.Yun Xiang,* Xiaoqing Qian, Bingying Jiang, Yaqin Chai, Ruo Yuan,* An aptamer-based signal-on and multiplexed sensing platform for one-spot simultaneous electronic detection of proteins and small molecules, Chemical Communications, 2011, 47, 4733–4735.

28.Yun Xiang,* Xiaoqing Qian, Ying Chen, Yuyong Zhang, Yaqin Chai, Ruo Yuan,* A reagentless and disposable electronic genosensor: from multiplexed analysis to molecular logic gates, Chemical Communications, 2011, 47, 2080–2082.

29.Ying Chen, Bingying Jiang, Yun Xiang,* Yaqin Chai, Ruo Yuan,* Aptamer-based highly sensitive electrochemiluminescent detection of thrombin via nanoparticle layer-by-layer assembled amplification labels, Chemical Communications, 2011, 47, 7758–7760.

30.Haixia Zhang, Bingying Jiang, Yun Xiang,* Jiao Su, Yaqin Chai, Ruo Yuan,* DNAzyme-based highly sensitive electronic detection of lead via quantum dot-assembled amplification labels, Biosensors & Bioelectronics, 2011, 29, 135–138.

31.Yun Xiang,* Xiaoqing Qian, Yuyong Zhang, Ying Chen, Yaqin Chai, Ruo Yuan,* A reagentless, disposable and multiplexed electronic biosensing platform: Application to molecular logic gates, Biosensors & Bioelectronics, 2011, 26, 3077–3080.

32.Haixia Zhang, Bingying Jiang, Yun Xiang,* Yuyong Zhang, Yaqin Chai, Ruo Yuan,* Aptamer/quantum dot-based simultaneous electrochemical detection of multiple small molecules, Analytica Chimica Acta, 2011, 688, 99–103.

33.Yun Xiang,* Yuyong Zhang, Bingying Jiang, Yaqin Chai, Ruo Yuan,* Multi-enzyme layer-by-layer assembly for dual amplified ultrasensitive electronic detection of cancer biomarkers, Sensors and Actuators, B 2011, 15, 317–322.

34.Yuyong Zhang, Yun Xiang,* Yaqin Chai, Ruo Yuan,* Xiaoqing Qian, Haixia Zhang, Gold nanolabels and enzymatic recycling dual amplification-based electrochemical immunosensor for the highly sensitive detection of carcinoembryonic antigen, Sci. China Ser. B 2011, 54, 1770–1776.

35.Yun Xiang,* Yuyong Zhang, Yue Chang, Yaqin Chai, Joseph Wang,* Ruo Yuan,* Reverse-micelle synthesis of electrochemically encoded quantum dot barcodes: Application to electronic coding of a cancer marker, Analytical Chemistry, 2010, 82, 1138–1141.

36.Xiaoqing Qian, Yun Xiang,* Haixia Zhang, Ying Chen, Yaqin Chai, Ruo Yuan,* Aptamer/nanoparticle-based sensitive, multiplexed electronic coding of proteins and small biomolecules through a backfilling strategy, Chemistry-An European Journal, 2010, 16, 14261–14265.

37.Yun Xiang,* Yuyong Zhang, Xiaoqing Qian, Yaqin Chai, Joseph Wang, Ruo Yuan,* Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic strategy, Biosensors & Bioelectronics, 2010, 25, 2539–2542.

38.Yuyong Zhang, Yun Xiang,* Yaqin Chai, Ruo Yuan,* Aptamer-based competitive electrochemical assay of small biomolecules, Sci. China Ser. B 2011, 54, 822–826.

39.Siriwan Suwansa-ard, Yun Xiang, Ralph Bash, Panote Thavarungkul, Proespichaya Kanatharana, Joseph Wang,* Prussian blue dispersed sphere catalytic labels for amplified electronic detection of DNA, Electroanalysis 2008, 20, 308–312.

40.Apon Numnuam, Karin Y. Chumbimuni-Torres, Yun Xiang, Ralph Bash, Panote Thavarungkul, Proespichaya Kanatharana, Erno1 Pretsch,* Joseph Wang,* Eric Bakker,* Aptamer-based potentiometric measurements of proteins using ion-selective microelectrodes, Analytical Chemistry, 2008, 80, 707–712.

41.Apon Numnuam, Karin Y. Chumbimuni-Torres, Yun Xiang, Ralph Bash, Panote Thavarungkul, Proespichaya Kanatharana, Erno1 Pretsch,* Joseph Wang,* Eric Bakker,* Potentiometric detection of DNA hybridization, Journal of the American Chemical Society, 2008, 130, 410–411.

42.Zong Dai, Abdel-Nasser Kawde, Yun Xiang, Jeffrey T. La Belle, Jared Gerlach, Veer P. Bhavanandan, Lokesh Joshi,* Joseph Wang,* Nanoparticle-based sensing of glycan-lectin interactions, Journal of the American Chemical Society, 2006, 128, 10018–10019.

43.Jacob A. Hansen, Joseph Wang,* Abdel-Nasser Kawde, Yun Xiang, Kurt V. Gothelf, Greg Collins, Quantum-dot/aptamer-based ultrasensitive multi-analyte electrochemical biosensor, Journal of the American Chemical Society, 2006, 128, 2228–2229.

44.Karin Y. Chumbimuni-Torres, Zong Dai, Nastassia Rubinova, Yun Xiang, Erno Pretsch,* Joseph Wang,* Eric Bakker*, Potentiometric biosensing of proteins with ultrasensitive ion-selective microelectrodes and nanoparticle labels, Journal of the American Chemical Society, 2006, 128, 13676–13677.

45.Anchana Preechaworapun, Zong Dai, Yun Xiang, Orawon Chailapakulb,* Joseph Wang,* Investigation of the enzyme hydrolysis products of the substrates of alkaline phosphatase in electrochemical immunosensing, Talanta, 2008, 76, 424–431.