華中農業大學植物科學技術學院導師介紹：廖玉才

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基本信息姓名: 廖玉才 出生年月: 1954.4
性別: 男 碩/博導： 博導
民族: 漢 開設課程： 分子生物學、遺傳學
職稱: 教授 研究方向： 1. 麥類作物基因工程; 2.真菌毒素形成與控制分子機理; 3. 植物生物反應器
學位: 自然科學博士

聯系方式 辦公電話：027-87283008
電子郵件：yucailiao@mail.hzau.edu.cn

個人簡介1983年獲華中農業大學作物遺傳育種專業碩士學位，1989年荷蘭瓦赫寧根大學訪問學者，1990-1994年德國亞琛大學分子遺傳研究所博士生，1994年獲德國亞琛大學分子生物學博士學位；1995-1996年為該所博士后，1997年回國，1998-2002年每年到德國亞琛大學分子生物技術所或英國約翰英納斯所開展合作科研。主要從事麥類作物抗赤霉病基因工程、鐮刀菌毒素形成與控制分子機理、重組抗體分離與表達分析、植物生物反應器等研究，在《Nature Biotechnology》、《Journal of Proteome Research》、《Fungal Genetics and Biology》、《Phytopathology》、《Plant Cell Report》、《Mycological Research》、《遺傳學報》等國內外專業期刊發表論文80多篇，已被引用700多次；獲省部級一等獎1項、三等獎1項，獲授權專利5項，申請專利7項，參編專著教材3部。現為《農業生物技術學報》和《麥類作物學報》編委，《中國農業科技導報》理事，湖北省新世紀高層次人才人選。在讀研究生30余人，外籍博士生4人

科研項目1. 國家自然科學基金重點項目：基于抗體的植物真菌病害分子控制原理與技術研究
2. 國家自然科學基金面上項目：抗體及其融合分子介導的抗赤霉病基因工程
3. 國家自然科學基金面上項目：我國小麥赤霉病菌的遺傳多樣性及致病性和產毒性的分子基礎
4.“十一”五國家科技支撐計劃：食品安全關鍵技術研究用
5. 農業部948項目：重組抗體及其融合分子介導的植物真菌病害控制技術引進與應用
6. 教育部博士點基金：抗體基因工程及在作物赤霉病抗性改良中的應用
7. 科技部863項目：動植物生物反應器新技術研究
8. 中-俄合作項目：植物抗體的表達及在植物抗病基因工程中的應用
9. 中-德合作項目：抗體融合蛋白防控植物和植物產品中黃曲霉菌及其毒素的研究
10. 農業部重大專項：抗赤霉病轉基因小麥新品系和新種質創制
11. 科技部973課題：有害物質從飼料污染到畜禽產品殘留的傳遞規律研究
12. 農業部重點課題：轉基因小麥快速甄別及高通量檢測技術
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發明專利及獲獎情況授權專利：
1. Molecular pathogenicide mediated plant disease resistance. US Patent Number 6825325 B1, Issued on Nov. 30, 2004.
2. Molecular pathogenicide mediated plant disease resistance. Indian Patent Number 192141, Issued on Aug. 17, 2004
3. 鐮刀菌毒素的分子檢測方法及應用. 專利號：ZL 200410009300.2; 授權日：2007.4.15
4. 一種非抗生素篩選小麥轉基因植物的方法. 授權日：2010.10.19
5. 一種農桿菌介導的無抗生素篩選轉基因大麥植株的方法. ZL 2007 1 0051390.5; 授權日：2010.5.19

獲獎：
1. 小麥抗赤霉病性遺傳及體細胞抗病突變體的選育，國家教委科技進步三等獎，1995
2. 食品及食品接觸材料有害殘留的高通量表征及安全性評價技術，國家質量監督檢驗檢疫總局科技興檢獎一等獎，2010

發表的論文及著作1. Chen, F.-F., Zhang, J. T., Song, X.-S., Yang, J., Li H.-P., Tang, H., Liao, Y.-C*. Combined metabonomic and reverse transcription PCR analyses reveals systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion. Journal of Proteome Research, 2011, in press. (﹡通訊作者)
2. Cheng, L., Li, H.-P., Qu, B., Huang, T., Tu, J.-X., Fu, T.-D., Liao, Y.-C*. Chloroplast transformation of rapeseed (Brassica napus) by particle bombardment of cotyledons. Plant Cell Reports, 2010, 29, 37:371-381.　
3. Li, X., Zhang, J. B., Song, B., Li, H. P., Xu, H. Q., Qu, B., Dang, F. J., Liao, Y. C*. Resistance to Fusarium head blight and seedling blight in wheat is associated with activation of a cytochrome P450 gene. Phytopathology, 2010, 100:183-191.
4. Xu, Y.-B., Li, H.-P., Zhang, J.-B., Song, B., Chen, F.-F., Duan, X.-J., Xu, H.-Q., Liao, Y.-C*. Disruption of the chitin synthase gene Chs1 from Fusarium asiaticum results in an altered structure of cell walls and reduced virulence. Fungal Genetics and Biology, 2010, 47: 205-215.
5. Li, H.-P., Huang, T., Wang, C.-X., Liao, Y.-C*. An efficient regeneration system of barley cultivars from leaf base segments. Biologia Plantarum, 2009, 53: 733-736.
6. Li, H.-P., Zhang, J.-B., Shi, R.-P., Huang, T., Fischer, R., Liao, Y.-C*. Engineering Fusarium head blight resistance in wheat by expression of a fusion protein containing a Fusarium-specific antibody and an antifungal peptide. Molecular Plant-Microbe Interaction, 2008, 21:1242-1248.
7. Wang, J.-H., Li, H.-P., Qu, B., Zhang, J.-B., Huang, T., Chen, F.-F., Liao, Y.-C*. Development of a generic PCR detection of 3-acetyldeoxynivalenol-, 15-acetyldeoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum clade. International Journal of Molecular Sciences, 2008, 9:2495-2504.
8. Li, H.-P., Zhang, J.-B., Qu, B., Huang, T., Chen, F.-F., Xu, Y.-B., Wu, A.-B., P. Nicholson, Liao, Y.-C*. Phylogenetic species, mycotoxin chemotypes and geographical distribution of Fusarium asiaticum and F. graminearum on wheat spikes throughout China. Journal of Plant Pathology, 2008, 90:3-S3, 89.
9. Hu, Z.-Q., Li, H.-P., Zhang, J.-B., Glinka, E., Liao, Y.-C*. Antibody-mediated prevention of Fusarium mycotoxins in the field. International Journal of Molecular Sciences, 2008, 9: 1915-1926.
10. Qu, B., Li, H.-P., Zhang, J.-B., Xu, Y.-B., Huang, T., Wu, A.B., Zhao, C.-S., Carter, J., Nicholson, P., Liao, Y.-C*. Geographical distribution and genetic diversity of the Fusarium graminearum and F. asiaticum on wheat spikes throughout China. Plant Pathology, 2008, 57: 15-24.
11. Qu, B., Li, H.-P., Zhang, J.-B., Huang, T., Carter, J., Liao, Y.-C*., P. Nicholson. Comparison of genetic diversity and pathogenicity of Fusarium head blight pathogens from China and Europe revealed by SSCP and seedling assays on wheat. Plant Pathology, 2008, 57:642-651.
12. Zhang, J.-B., Li, H.-P., Dang, F.-J., Qu, B., Xu, Y.-B., Zhao, C.-S., Liao, Y.-C*. Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China. Mycological Research, 2007, 111:967-975.
13. Liao, Y.-C*., Li, H.-P., Zhao, C.-S., Yao, M.-J., Zhang, J.-B., Liu, J.-L. Plantibodies: A novel strategy to create pathogen-resistant plants. Biotechnology and Genetic Engineering Reviews, 2006, 23:253-271.
14. Li, H.-P., Wu, A.-B., Zhao, C.-S., Scholten, O., Loeffler, H., Liao, Y.-C*. Development of a generic PCR detection of deoxynivalenol- and nivalenol-chemotypes of Fusarium graminearum. FEMS Microbiology Letters, 2005, 243:505-511.
15. Wu, A.-B.，Li., H.-P., Zhao, C.-S., Liao, Y.-C*. Comparative pathogenicity of Fusarium graminearum from China revealed by wheat coleoptile and floret inoculations. Mycopathologia, 2005, 160:75-83.
16. Peschen, D., Li, H.-P., Fischer, R., Kreuzaler, F., Liao, Y.-C*. Fusion proteins comprising a Fusarium-specific antibody linked to anti-fungal peptides protect plants against fungal pathogens. Nature Biotechnology, 2004, 22:732-738.
17. Li, H.-P., Fu, C.-Y., Fischer, R., Liao, Y.-C*. Cloning and characterization of a gene coding for a class I chitin synthase from Fusarium graminearum. Canadian Journal of Plant Pathology, 2003, 25:240-248.
18. Li, H.-P., Fischer, R., Liao, Y.-C*. Molecular evidence for induction of phenylalanine ammonia lyase during Puccinia graminis infection and elicitation in wheat. Canadian Journal of Plant Pathology, 2001, 23:286-291.
19. Zhang, M.-Y., Schillberg, S., Zimmermann, S., Liao, Y.-C., Breuer, G., Fischer, R. GST fusion proteins could cause false positive in screening phage-displayed antibody fragments. Journal of Virological Methods, 2001, 91:139-147.
20. Fischer, R., Liao, Y.-C., Drossard, J. Affinity-purification of a TMV-specific recombinant full-size antibody from a transgenic tobacco suspension culture, Journal of Immunological Methods, 1999, 226:1-10.
21. Fischer, R., Liao, Y.-C., Hoffmann, K., Schillberg, S., Emans, N. Molecular farming of recombinant antibodies in plants. Biological Chemistry, 1999, 380, 7/8:825-839.
22. Spiegel, H., Schillberg, C., Sack, M., Holzem, A., Liao, Y.-C., Fischer, R. Accumulation of antibody fusion proteins in the cytoplasm and ER of plant cells. Plant Science, 1999, 146:1-9.
23. Zimmermann, S., Schillberg, S., Liao, Y.-C., Fischer, R. Intracellular expression of TMV-specific single chain Fv fragments leads to improved virus resistance in Nicotiana tabacum. Molecular Breeding, 1998, 4: 369-379.
24. Vaquero-Martin, C., Liao, Y.-C., Fischer, R. Use of non-radiactive probes to study protein-nucleic acids interactions by U.V.-crosslinking. Biotechniques, 1998, 24: 68-70.