蘭州大學生命科學學院導師介紹：陳強

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學習經歷

1997－2001 蘭州大學生命科學學院生物化學專業 博士
1995－1996 意大利國家野生動物研究所（Istituto Nazionale per la Funa Selvatica）訪問學者
1987－1990 蘭州大學生物系動物學專業 碩士
1979－1983 蘭州大學生物系動物學專業 學士
 
工作經歷

2004- 蘭州大學生命科學學院 教授
2004-2010 蘭州大學生命科學學院副院長
2006－蘭州大學生物學實驗教學中心（國家級實驗教學示范中心）主任
1997-2004 蘭州大學生命科學學院 副教授
1990-1997 蘭州大學生物系 講師
1983-1990 蘭州大學生物系 助教

教學及指導研究生情況

在讀博士研究生4名，碩士研究生9名。已畢業博士研究生1名，碩士研究36名。

發表論文及專著

Yang, S., Yang, A., Shao, T., Su, S., Chen, Q.* (2013) Synergistic analgesic effects between neuronostatin and morphine at thesupraspinal level. Peptides 44: 105– 110
Lv, S., Yang, Y., Chen, Q.* (2013) Regulation of feeding behavior, gastrointestinal function and fluid homeostasisby apelin. Peptides 44: 87– 92
He, J., Xiu, M., Tang, X., Wang, N., Xin, Y., Chen, Q.* (2013) Theroregulatory and metabolic responses to hypoxia in the oviparous lizards, Phrynocephalus przewalskii. Comp Biochem Physiol A 165: 207-213
He, J., Xiu, M., Tang, X., Yue, F., Wang, N., Chen, Q.* (2013) The different mechanisms of hypoxic acclimatization and adaptation in lizard Phrynocephalus vlangalii living on Qinghai-Tibet Plateau. J EXP ZOOL PART A 319(3): 117-123
Tang, X., Yue, F., Ma, M., Wang, N., He, J., Chen, Q.* (2012) Effects of Thermal and Hydric Conditions on Egg Incubation and Hatchling Phenotypes in Two Phrynocephalus Lizards. Asian Herpetological Research 3(3): 184-191
Tang, X., Yue, F., Zhang, D., Yan, X., Xin, Y., Wang, C., Chen, Q.* (2012) The effect of operational sex ratio on sex allocation and neonate phenotype in a viviparous lizard Eremias multiocellata Amphibia-Reptilia 33: 485-493
Su, S., Yang, A., Yang, S., Wang, N., Lu, S., Wang, H., Chen, Q.*　(2012) Intracerebroventricular administration of neuronostatin delays gastric emptying　and gastrointestinal transit in mice.　Peptides 35: 31–35
Lv, S., Qin, Y., Wang, H., Xu, N., Yang, Y., Chen, Q.* (2012) Centrally administered apelin-13 induces depression-like behavior in mice. Brain Res Bull 88(6):574-80.
Tang, X., Yue, F., Yan, X., Zhang, D., Xin, Y., Wang, C., Chen, Q.* (2012) Effects of gestation temperature on offspring sex and maternal reproduction in aviviparous lizard (Eremias multiocellata) living at high altitude. Journal of Thermal Biology 37: 438–444
Yang, S., Yang, A., Su, S., Wang, H., Wang, N., Chen, Q.* (2012) Neuronostatin induces hyperalgesia in formalin test in mice. Neuroscience Letters 506: 126–130
Lv, S., Yang, Y., Qin, Y., Mo, J., Wang, N., Wang, Y., Chen, Q.* (2012) Central apelin-13 inhibits food intake via the CRF receptor in mice. Peptides 33: 132-138
Yue, F., Tang, X., Zhang, D., Yan, X., Xin, Y., Chen, Q.* (2012) Body temperature and standard metabolic rate of female viviparous lizard Eremias multiocellata during reproduction. Canadian Journal of Zoology 90: 79–84
Xin, Y., Tang, X., Yue, F., Zhang, D., Yan, X., Wang, C., Chen, Q.* (2012) Isolation and Sequence Analysis of Sox Genes from lizard Eremias multiocellata. Russian Journal of Genetics 48(1): 88-94
Yang, A., Ji, Y., Su, S., Yang, S., Lu, S., Mi, Z., Yang, Q., Chen, Q.* (2011) Intracerebroventricular administration of neuronostatin induces depression-like effect in forced swim test of mice. Peptides 32: 1948–1952
Yang, A., Ge, W., Lu, S., Yang, S., Su, S., Mi, Z., Chen, Q.* (2011) Central administration of neuronostatin induces antinociception in mice. Peptides 32: 1893–1901
Yan, X., Tang, X., Yue, F., Zhang, D., Xin, Y., Wang, C., Chen, Q.* (2011) Influence of ambient temperature on maternal thermoregulation and neonate phenotypes in a viviparous lizard, Eremias multiocellata, during the gestation period. Journal of Thermal Biology 36: 187–192
呂雙瑜 楊愛民 修明慧 楊艷杰 陳強*(2011) 側腦室注射脂肪酸合成酶抑制劑C75對小鼠學習記憶的影響，中華行為醫學與腦科學雜志 20（1）：51-52
Lv, S., Yang, Y., Qin, Y., Xiong, X., Chen, Q.* (2011) Effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in mice. Peptides 32: 978–982
Yang, Q., Lu, S., Tian, X., Yang, A., Ge, W., Chen, Q.* (2011) The antidepressant-like effect of human opiorphin via opioid-dependent pathways in mice. Neuroscience Letters 489: 131-135
Yang, Y., Lv, S., Xiu, M., Xu, N., Chen, Q.* (2010) Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice. Peptides 31: 2241–2246
Zhang, D., Yue, F., Tang, X., Chen, Z., Li, R., Chen, Q.* (2010) Effect of gestation temperature on sexual and morphological phenotypes of offsprings in a viviparous lizard, Eremias multiocellata. Journal of Thermal Biology 35: 129–133
Tian, X., Chen, J., Xiong, W., He, T., Chen, Q.* (2009) Effects and underlying mechanisms of human opiorphin on colonic motility and nociception in mice. Peptides 30:1348-54
Xu, N., Wang, H., Fan, L., Chen, Q.* (2009) Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice. Peptides 30: 1153–1157
Li, L., Lu, Y., Xiong, W., Liu, J., Chen, Q.* (2008) Effect of centrally administered C75, a fatty acid synthase inhibitor, on gastric emptying and gastrointestinal transit in mice. European Journal of Pharmacology 595: 90–94
Chen, J., Long, Y., Han, H., Wang, T., Chen, Q.,* Wang, R.* (2008) Water-solutable derivates of propolis mitigates scopolamine-induced learning and memory impairment in mice. Pharmacology, Biochemistry and Behavior 90:441-446
Zai, K., Hu, L., Chen, J., Fu, C., Chen, Q.* (2008) Chrysin induced hyperalgesia via GABAA receptor in mice. Planta Medica 74:1229-1234
歐陽建梅 隴源 房克難 王銳 陳強*, (2007) 蜂膠乙醇提取物(EEP)對豚鼠胸主動脈的舒張作用, 現代生物醫學進展 (9):1286-1289
Zhao, Q., Chen, Q., Feng, Y., Lin,X., Wang, R.* (2005) [TIC4] endomorphins, analogues of endomorphins, have significantly　nhanced vasorelaxant effects in rat aorta rings. Protein Pept. Lett 12(4), 323-326
Xu, P., Chen, Q., Li, H., Yu, Y., Yan, X., Wang, R.* (2005) The relaxant effect of dobutamine on porcine coronary arterial ring segments. Pharmazie 60 375-377
Feng, Y., Zhao, Q., Chen, Q., Wang, R.* (2005) Vasorelaxant responses to endomorphin1[ ], analogues of endomorphins, in rat aorta rings.Yand endomorphine2[ pharmazie 60:851-855
Fu, C., Kong, Z., Wang, K., Yang, Q., Zhai, K., Chen, Q.,*　Wang, R.*　(2005) Effects and mechanisms of supraspinal administration of rat/mouse　hemokinin-1, a mammalian tachykinin peptide, on nociception in mice. Brain Research 1056, 51-58
Zhao, Q., Chen, Q., Yang, D., Feng, Y., Long, Y., Wang, P., Wang, R.* (2005) Endomorphin 1[c] and endomorphin 2[c], endomorphins analogues containing a reduced (CH2NH) amide bond between Tyr1 and Pro2, display partial agonist potency but significant antinociception. Life Sci., 77, 1155-1165
Xu, P., Chang, M., Chen, L., Chen, Q.,* Yan, X.,* Wang, R.* (2004) The relaxant Effect of nociceptin on porcine coronary arterial ring segment. Can. J. Physiol. Pharmacol 82, 993-999
Lin, X., Chen, Q., Xue, L., Ma, X., Wang, R.* (2004) Endomorphins, endogenous opioid peptides induce apoptosis in human leukemia HL-60 cells. Can. J. Physiol. Pharmacol 82, 1018-1025
Chen, L., Fang, Q., Chen, Q.,* Guo, J., Wang, Z., Chen, Y., Wang, R. * (2004) Study in vitro and in vivo of nociceptin/orphanin FQ(1–13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3. Peptides 25, 1349-1354
Lin, X., Cai, Y., Li, Z., Chen, Q., Wang, R.*(2003) Structure determination, apoptosis induction, and telomerase inhibition of CFP-2, a novel lichenin from Cladonia furcata. Biochim. Biophys. Acta 1622: 99
Lin, X., Yang, D., Cai, W., Zhao, Q., Gao, Y., Chen, Q., Wang, R.* (2003) Endomorphins, endogenous opioid peptide, provide antioxidant defense in the brain against free radicall-induced damage. Biochim. Biophys. Acta (BBA)-Mol. Basis. Dis 1639: 195
Chen, Q., Chen, Y., Chen, L., Yang, D., Dong, S., Wang, R.* (2001) The effects of the synthetic nocistation on blood vessel activities. Chin. Sci. Bull 46(8): 275
吳寧, 霍笑風, 陳強, 楊頂建, 王 銳* (2001) 側腦室注射內嗎啡肽-1對麻醉大鼠血壓的影響. 藥學學報 36(10): 731"
吳寧, 任維華, 霍笑風, 陳強, 王 銳* (2001) 內嗎啡肽及其類似物對心血管系統的作用. 藥學學報 36(4): 241
陳勇, 陳鯉翔, 陳強, 楊頂建, 彭雅麗, 楊祺, 王 銳* (2001) 痛穩素碳末端八肽翻轉孤啡肽對抗嗎啡鎮痛的作用. 中國藥理學通報17(4): 383
Chen, Q., Chen, L., Chen, Y., Yang, D., Peng, Y., Dong, S., Wang, R.* (2000) Effects of the synthesized nocistatin and nocistatin (10-17) on analgesia induced by endomorphin-1 and endomorphin-2. Acta Pharmacol. Sin 21(11): 1053"
陳強, 陳勇, 陳鯉翔, 楊頂建, 董守良, 王 銳* (2000) 痛穩素的合成及其對血管活性的影響. 科學通報 45(24): 2620）
Chen, Q., Chang, C., Liu, N., E. Randi, V. Licchini, Mitochondrial DNA intro-gression between two parapatric species (Alectoris) in Central China動物學報1999,45(4):456
陳強, 李仁德, 劉迺發, (1999) 雄性密點麻蜥精巢支持細胞和間質細胞的年周期變化. 蘭州大學學報 35(專輯)80-82
Li, R., Chen, Qiang., Liu, N. (1998) Effects of body temperature on electrocardiograms of lizard Eremias multiocellata. 動物學研究 19(4): 269-276
李仁德, 陳強, 劉迺發, (1996) 溫度對蜥蜴血紅蛋白及血漿總蛋白濃度的影響, 動物學報, 42(3):247-252
陳強, (1995) 麗斑麻蜥和草原沙蜥靜止代謝率的研究, 蘭州大學學報(自然科學版), 31(1):68-71
陳強, 韓昭雪, (1993) 變色沙蜥繁殖的研究, 蘭州大學學報(自然科學版) 29(4):199- 204

研究方向

肽類激素或其它多肽的生物學活性與作用機理
蜥蜴對干旱、高寒、缺氧等環境的適應機制

項目成果

密點麻蜥性別決定機制的研究國家自然科學基金面上項目，2007.1-2009.12，（主持）
三種沙蜥的性別決定機制以及孵化溫度對其幼體生存能力影響的研究國家自然科學基金面上項目，2011.1－2011.12（主持）
若干多肽合成和化學修飾的新方法和關鍵技術及其在多肽藥物產業開發中的應用國家科技重大專項 2009.1-2010.12（參加）
青海沙蜥和紅尾沙蜥對高原低氧的適應機制研究　國家自然科學基金面上項目，2013－2016（主持） 
 

榮譽、獲獎

蘭州大學2009年教書育人先進個人
甘肅省高等學校實驗室建設與管理先進工作者 2006
甘肅省教學成果二等獎生物學實驗技術隊伍建設與本科生創新能力培養模式及實踐（排名第二） 2010
甘肅省教學成果二等獎生物學野外實習改革與實踐（排名第二）2008
甘肅省自然科學二等獎我國石雞屬鳥類分類、生態和生態遺傳研究（排名第三） 2007

社會工作

中國生物化學與分子生物學會第十屆理事會理事 2010.8－2014.8
中國生理學會比較生理學專業委員會委員 2008－
教育部高等學校生物科學與工程教學指導委員會委員2006-2010
其它信息 教學工作

主講課程：動物生理學、生命科學導論、人體解剖生理學

教育部雙語教學示范課程“動物生理學”（負責人）

甘肅省精品課程“動物生理學”（負責人）

甘肅省精品課程“生命科學導論”（負責人）

主持三項國家自然科學基金委“基礎科學人才培養基金”項目

編寫教材與著作

梅巖艾等主編 生理學原理 高等教育出版社 2011 （編者之一）

李仁德 董守良 陳強 人體及動物生理學實驗指導 蘭州大學出版社 2003

陳強郭吉軍 沙漠與動物 甘肅少兒出版社 1999