蘭州大學基礎醫學院導師介紹：閻文錦

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閻文錦：副教授，碩士生導師，于1993年從山西平遙考入蘭州大學化學系就讀于應用化學專業，在1997年6月本科畢業后進入秦山第三核電有限公司工作。在秦山工作5年后，于2002年考入蘭州大學生命科學學院。主要從事含氮有機小分子化合物藥物化學及藥理學研究。
郵箱   yanwj@lzu.edu.cn

教育經歷

1993.9 - 1997.6   蘭州大學應用化學, 學士
2002.9 - 2007.6   蘭州大學生物化學與分子生物學，博士

工作經歷

2010-2012蘭州大學基礎醫學院講師
2012- 蘭州大學基礎醫學院受聘為副教授、碩士生導師

研究領域

不對稱催化，手性藥物合成及藥理學研究

主持的在研項目

1.中央高校基本科研業務費“含α-CF3胺結構單元的氨基酸的合成研究” （lzujbky-2013-168 ）， 2013.1-2014.6
2. 國家自然科學基金面上項目“3-烷氧羰基靛紅亞胺的合成及其在合成手性雙取代3-氨基氧化吲哚化合物方面的應用 ” ( No. 21272108 ), 2013-2016

代表性論著:

1.Dong Wang1, Jinyan Liang1, Jingchao Feng, Kairong Wang, Quantao Sun, Long Zhao, Dan Li, Wenjin Yan*, Rui Wang*（The Quinine Thiourea-catalyzed Asymmetric Strecker Reaction: An Approach for the Synthesis of 3-Aminooxidoles）advanced Synthesis & Catalysis 2013,355:548-58. (SCI 二區, IF 6.048）
2. Jingchao Feng, Wenjin Yan, Dong Wang, Peng Li, Quantao Sun， Rui Wang (The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids) Chem. Commun.,  2012, 48, 8003.  (SCI二區, IF 6.169）
3. Wenjin Yan, Dong Wang, Jingchao Feng, Peng Li, Rui Wang (The Synthesis of N-Alkoxycarbonyl Ketimines Derived from Isatin and Their Application in Enantioselective Transformations) Org . Lett.  2012, 14, 2512   (SCI二區, IF 5.862）
4. Wenjin Yan; Dong Wang, Jingchao Feng, Peng Li, Rui Wang（Zinc-Mediated Diastereoselective Synthesis of 3-Amino Oxindoles by Addition of Methyl and Terminal Alkynes to N-tert-Butanesulfinyl Ketimines） J. Org. Chem. 2012,  2012, 77, 3311.  (SCI二區, IF 4.45）.
5．Wenjin Yan, Peng Li, Jingchao Feng, Dong Wang, Xianxing Jiang,Shaoqun Zhu, and Rui Wang (Design and Synthesis of Tridentate Ligand Inspired by the Phenomenon of Self-assembly Catalysis and its Application in Asymmetric Alkynylation of N-(diphenylphosphinoyl) Imines) Tetrahedron: Asymmetry 2010, 2037-2042. (SCI三區, IF 2.625）.
6．Shaoqun Zhu, Wenjin Yan, Bin Mao, Xianxing Jiang, Rui Wang. Enantioselective Nucleophilic Addition of Trimethylsilylacetylene to N-Phosphinoylimines Promoted by C2-Symmetric Proline–Derivatived β-Amino Alcohol. J. Org. Chem. 2009, 6980-6985. (SCI二區, IF 4.45）
7．Wenjin Yan, Bin Mao, Shaoqun Zhu, Xianxing Jiang, Zhongli Liu, and Rui Wang. Asymmetric Addition of Terminal Alkynes to N-(diphenylphosphinoyl) Imines Promoted by Stoichiometric Amount Proline-Derived β-Amino Alcohol. Eur. J. Org. Chem. 2009, 3790-3794.
(SCI三區, IF 3.20 )
8.  K Wang, J Yan, W Dang, X Liu, R Chen, J Zhang, B Zhang, W Zhang, M Kai, Wenjin Yan, Z Yang, J Xie, Rui Wang. Membrane active antimicrobial activity and molecular dynamics study of a novel cationic antimicrobial peptide polybia-MPI, from the venom of Polybia paulista. Peptides 2013, 39,80–88. （SCI三區，IF=2.421）